Literature DB >> 29533614

Diastereoselective Construction of Indole-Bridged Chroman Spirooxindoles through a TfOH-Catalyzed Michael Addition-Inspired Cascade Reaction.

Jiaomei Guo1, Xuguan Bai1, Qilin Wang1, Zhanwei Bu1.   

Abstract

The first highly diastereoselective Michael addition/condensation/Friedel-Crafts alkylation cascade reaction of 3-indolyl-substituted oxindoles with ortho-hydroxychalcones was established, which afforded a wide range of polycyclic indole-bridged chroman spirooxindoles with novel and complex scaffolds in moderate to excellent yields.

Entities:  

Year:  2018        PMID： 29533614     DOI： 10.1021/acs.joc.8b00035

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

Review 1.  Principle and design of pseudo-natural products.

Authors:  George Karageorgis; Daniel J Foley; Luca Laraia; Herbert Waldmann
Journal:  Nat Chem       Date:  2020-02-03       Impact factor: 24.427

2.  Diastereoselective construction of 4-indole substituted chromans bearing a ketal motif through a three-component Friedel-Crafts alkylation/ketalization sequence.

Authors:  Jiao-Mei Guo; Wen-Bo Wang; Jia Guo; Yan-Shuo Zhu; Xu-Guan Bai; Shao-Jing Jin; Qi-Lin Wang; Zhan-Wei Bu
Journal:  RSC Adv       Date:  2018-04-25       Impact factor: 3.361

3.  A bio-inspired synthesis of hybrid flavonoids from 2-hydroxychalcone driven by visible light.

Authors:  Yu-Qi Gao; Yi Hou; Liming Zhu; Guzhou Chen; Dongyang Xu; Sheng-Yong Zhang; Yupeng He; Weiqing Xie
Journal:  RSC Adv       Date:  2019-09-16       Impact factor: 4.036
  3 in total

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