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Literature DB >> 29532847

In vivo and in vitro identification of Z-BOX C - a new bilirubin oxidation end product.

Marcel Ritter¹, Sandesh Neupane, Raphael A Seidel, Christoph Steinbeck, Georg Pohnert.

Abstract

A new bilirubin oxidation end product (BOX) was isolated and characterized. The formation of the so-called Z-BOX C proceeds from bilirubin via propentdyopents as intermediates. This BOX was detected in pathological human bile samples using liquid chromatography/mass spectrometry and has potential relevance for liver dysfunction and cerebral vasospasms.

Entities: Chemical Disease Species

Mesh：

Substances：
Bilirubin

Year: 2018 PMID： 29532847 DOI： 10.1039/c8ob00164b

Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876

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Cited

4 in total

1. A New Product of Bilirubin Degradation by H₂O₂ and Its Formation in Activated Neutrophils and in an Inflammatory Mouse Model.

Authors: Fei-Fei Yu; Yao Yuan; Yan Ao; Li Hua; Wu Wang; Yiyi Cao; Jing Xi; Yang Luan; Shangwei Hou; Xin-Yu Zhang
Journal: Biomolecules Date: 2022-09-04

In vivo and in vitro identification of Z-BOX C - a new bilirubin oxidation end product.

1. A New Product of Bilirubin Degradation by H₂O₂ and Its Formation in Activated Neutrophils and in an Inflammatory Mouse Model.

2. Bilirubin Oxidation Products and Cerebral Vasoconstriction.

3. Pyrrolic and Dipyrrolic Chlorophyll Degradation Products in Plants and Herbivores.

4. Bilirubin Oxidation End Products (BOXes) Induce Neuronal Oxidative Stress Involving the Nrf2 Pathway.

In vivo and in vitro identification of Z-BOX C - a new bilirubin oxidation end product.

1. A New Product of Bilirubin Degradation by H2O2 and Its Formation in Activated Neutrophils and in an Inflammatory Mouse Model.

2. Bilirubin Oxidation Products and Cerebral Vasoconstriction.

3. Pyrrolic and Dipyrrolic Chlorophyll Degradation Products in Plants and Herbivores.

4. Bilirubin Oxidation End Products (BOXes) Induce Neuronal Oxidative Stress Involving the Nrf2 Pathway.

1. A New Product of Bilirubin Degradation by H₂O₂ and Its Formation in Activated Neutrophils and in an Inflammatory Mouse Model.