Literature DB >> 29532759

Amlodipine (150 mg) Poisoning: A Case Study.

Annu Raj1, Prasan Kumar Panda1, Shiv Shankar Singh1.   

Abstract

BACKGROUND: Treatments of patients with amlodipine (a calcium channel blocker, CCB) overdose/poisoning remain challenging and death is certain if not intervened timely. Furthermore, for the society, the availability and common use of this drug can drive more vulnerable groups, especially children, towards an accidental/suicidal poisoning. CASE REPORT: Herein, we describe the case of an 18 year-old-adolescent girl who took 150 mg of amlodipine with the suicidal intentions and was admitted in our hospital approximately 4-hours after the ingestion. She developed circulatory failure and tachypnea. Decontamination, calcium, glucagon, and dual vasopressors were started, however, persistent hypotension led to the initiation of hyperinsulinemiceuglycemia therapy. She recovered fully and discharged without any complications in few days. This case educates not only about the successful use of variant drugs in the management of CCB overdose/poisoning, but also calls for the attention of the society for a safe storage of often used drugs, especially away from the children/adolescents. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  CCB; hyperinsulemiceuglycemic therapy; inotrope; overdose; refractory shock; suicide intention.

Mesh:

Substances:

Year:  2018        PMID: 29532759     DOI: 10.2174/1574886313666180313120659

Source DB:  PubMed          Journal:  Curr Drug Saf        ISSN: 1574-8863


  1 in total

Review 1.  Management of Calcium Channel Blocker Toxicity in the Pediatric Patient.

Authors:  Jenna W Bartlett; Pamela L Walker
Journal:  J Pediatr Pharmacol Ther       Date:  2019 Sep-Oct
  1 in total

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