Literature DB >> 29531025

Misrepresentation and distortion of research in biomedical literature.

Isabelle Boutron1,2,3, Philippe Ravaud4,2,3,5.   

Abstract

Publication in peer-reviewed journals is an essential step in the scientific process. However, publication is not simply the reporting of facts arising from a straightforward analysis thereof. Authors have broad latitude when writing their reports and may be tempted to consciously or unconsciously "spin" their study findings. Spin has been defined as a specific intentional or unintentional reporting that fails to faithfully reflect the nature and range of findings and that could affect the impression the results produce in readers. This article, based on a literature review, reports the various practices of spin from misreporting by "beautification" of methods to misreporting by misinterpreting the results. It provides data on the prevalence of some forms of spin in specific fields and the possible effects of some types of spin on readers' interpretation and research dissemination. We also discuss why researchers would spin their reports and possible ways to avoid it.

Entities:  

Keywords:  bias; detrimental research practice; misinterpretation; misreporting; misrepresentation

Mesh:

Year:  2018        PMID: 29531025      PMCID: PMC5856510          DOI: 10.1073/pnas.1710755115

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  81 in total

1.  Testing for the presence of positive-outcome bias in peer review: a randomized controlled trial.

Authors:  Gwendolyn B Emerson; Winston J Warme; Fredric M Wolf; James D Heckman; Richard A Brand; Seth S Leopold
Journal:  Arch Intern Med       Date:  2010-11-22

Review 2.  Users' guide to detecting misleading claims in clinical research reports.

Authors:  Victor M Montori; Roman Jaeschke; Holger J Schünemann; Mohit Bhandari; Jan L Brozek; P J Devereaux; Gordon H Guyatt
Journal:  BMJ       Date:  2004-11-06

3.  Multiplicity in randomised trials II: subgroup and interim analyses.

Authors:  Kenneth F Schulz; David A Grimes
Journal:  Lancet       Date:  2005 May 7-13       Impact factor: 79.321

4.  Belief beyond the evidence: using the proposed effect of breakfast on obesity to show 2 practices that distort scientific evidence.

Authors:  Andrew W Brown; Michelle M Bohan Brown; David B Allison
Journal:  Am J Clin Nutr       Date:  2013-09-04       Impact factor: 7.045

Review 5.  Converting an odds ratio to a range of plausible relative risks for better communication of research findings.

Authors:  Robert L Grant
Journal:  BMJ       Date:  2014-01-24

6.  Reporting of Randomized Controlled Trials With Statistically Nonsignificant Primary Outcomes Published in High-impact Surgical Journals.

Authors:  Lakshmanan Arunachalam; Iain A Hunter; Shane Killeen
Journal:  Ann Surg       Date:  2017-06       Impact factor: 12.969

Review 7.  Evidence for the selective reporting of analyses and discrepancies in clinical trials: a systematic review of cohort studies of clinical trials.

Authors:  Kerry Dwan; Douglas G Altman; Mike Clarke; Carrol Gamble; Julian P T Higgins; Jonathan A C Sterne; Paula R Williamson; Jamie J Kirkham
Journal:  PLoS Med       Date:  2014-06-24       Impact factor: 11.069

8.  Badges to Acknowledge Open Practices: A Simple, Low-Cost, Effective Method for Increasing Transparency.

Authors:  Mallory C Kidwell; Ljiljana B Lazarević; Erica Baranski; Tom E Hardwicke; Sarah Piechowski; Lina-Sophia Falkenberg; Curtis Kennett; Agnieszka Slowik; Carina Sonnleitner; Chelsey Hess-Holden; Timothy M Errington; Susann Fiedler; Brian A Nosek
Journal:  PLoS Biol       Date:  2016-05-12       Impact factor: 8.029

9.  Randomized trials published in some Chinese journals: how many are randomized?

Authors:  Taixiang Wu; Youping Li; Zhaoxiang Bian; Guanjian Liu; David Moher
Journal:  Trials       Date:  2009-07-02       Impact factor: 2.279

Review 10.  Complex interventions to improve physical function and maintain independent living in elderly people: a systematic review and meta-analysis.

Authors:  Andrew D Beswick; Karen Rees; Paul Dieppe; Salma Ayis; Rachael Gooberman-Hill; Jeremy Horwood; Shah Ebrahim
Journal:  Lancet       Date:  2008-03-01       Impact factor: 79.321

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  24 in total

1.  Reproducibility of research: Issues and proposed remedies.

Authors:  David B Allison; Richard M Shiffrin; Victoria Stodden
Journal:  Proc Natl Acad Sci U S A       Date:  2018-03-12       Impact factor: 11.205

2.  Spin in the abstract in "Impact of motivational interviewing on outcomes of an adolescent obesity treatment: Results from the MI Values randomized controlled pilot trial".

Authors:  Colby J Vorland; Andrew W Brown; David B Allison
Journal:  Clin Obes       Date:  2019-08-04

3.  Letter to the editor regarding "Does vitamin C supplementation improve rotator cuff healing? A preliminary study".

Authors:  Peter W Stubbs; Arianne P Verhagen; Alana B McCambridge
Journal:  Eur J Orthop Surg Traumatol       Date:  2021-06-11

4.  Publication Ethics.

Authors:  Pramod Kumar Singh; Vinay Kumar; Shahul Ameen; Sujit Sarkhel; Samir Kumar Praharaj; Vikas Menon
Journal:  Indian J Psychiatry       Date:  2022-03-22       Impact factor: 1.759

5.  A systematic search and qualitative review of reporting bias of lifestyle interventions in randomized controlled trials of diabetes prevention and management.

Authors:  Natalie D Riediger; Andrea E Bombak; Adriana Mudryj; Jackson Bensley; Samuel Ankomah
Journal:  Nutr J       Date:  2018-09-07       Impact factor: 3.271

6.  Occurrence and nature of questionable research practices in the reporting of messages and conclusions in international scientific Health Services Research publications: a structured assessment of publications authored by researchers in the Netherlands.

Authors:  Reinie G Gerrits; Tessa Jansen; Joko Mulyanto; Michael J van den Berg; Niek S Klazinga; Dionne S Kringos
Journal:  BMJ Open       Date:  2019-05-15       Impact factor: 2.692

7.  Three randomized controlled trials evaluating the impact of "spin" in health news stories reporting studies of pharmacologic treatments on patients'/caregivers' interpretation of treatment benefit.

Authors:  Isabelle Boutron; Romana Haneef; Amélie Yavchitz; Gabriel Baron; John Novack; Ivan Oransky; Gary Schwitzer; Philippe Ravaud
Journal:  BMC Med       Date:  2019-06-04       Impact factor: 8.775

8.  What's not in the news headlines or titles of Alzheimer disease articles? #InMice.

Authors:  Marcia Triunfol; Fabio C Gouveia
Journal:  PLoS Biol       Date:  2021-06-15       Impact factor: 8.029

9.  P-hacking in clinical trials and how incentives shape the distribution of results across phases.

Authors:  Jérôme Adda; Christian Decker; Marco Ottaviani
Journal:  Proc Natl Acad Sci U S A       Date:  2020-06-02       Impact factor: 11.205

10.  Trial registration as a safeguard against outcome reporting bias and spin? A case study of randomized controlled trials of acupuncture.

Authors:  Jiyoon Won; Seoyeon Kim; Inhu Bae; Hyangsook Lee
Journal:  PLoS One       Date:  2019-10-03       Impact factor: 3.240

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