Literature DB >> 29529421

Clozapine use in geriatric patients- Challenges.

Shiva Shanker Reddy Mukku1, P T Sivakumar2, Mathew Varghese3.   

Abstract

Clozapine is the first second generation antipsychotic with different receptor profile of action. Clozapine is the most efficacious drug for the treatment of psychotic disorder and is the drug of choice in treatment resistant schizophrenia. Clozapine is used in elderly patients infrequently owing to its adverse effects profile and tolerability. There is paucity of literature with respect to clozapine use in late life. In this narrative review, we discuss clozapine use in elderly and challenges associated with its use.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Clozapine; Cognition; Elderly; Parkinson’s disease; Schizophrenia

Mesh：

Substances：

Year:  2018        PMID： 29529421     DOI： 10.1016/j.ajp.2018.03.008

Source DB:  PubMed          Journal:  Asian J Psychiatr        ISSN： 1876-2018


  6 in total

Review 1.  [Psychiatric pharmacotherapy of older individuals with severe mental illness].

Authors:  Christian Lange-Asschenfeldt
Journal:  Z Gerontol Geriatr       Date:  2018-10-09       Impact factor: 1.281

Review 2.  [Diseases of the schizophrenia spectrum disorder in old age : Diagnostic and therapeutic challenges].

Authors:  Christian Jagsch; Alex Hofer
Journal:  Z Gerontol Geriatr       Date:  2018-08-14       Impact factor: 1.281

Review 3.  Clozapine: An Updated Overview of Pharmacogenetic Biomarkers, Risks, and Safety-Particularities in the Context of COVID-19.

Authors:  Ana Miruna Dragoi; Ioana Radulescu; Bogdana Adriana Năsui; Anca Lucia Pop; Valentin Nicolae Varlas; Simona Trifu
Journal:  Brain Sci       Date:  2020-11-11

4.  SkipGNN: predicting molecular interactions with skip-graph networks.

Authors:  Kexin Huang; Cao Xiao; Lucas M Glass; Marinka Zitnik; Jimeng Sun
Journal:  Sci Rep       Date:  2020-12-03       Impact factor: 4.379

5.  Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study.

Authors:  Martin Schulze Westhoff; Adrian Groh; Sebastian Schröder; Phileas Johannes Proskynitopoulos; Kirsten Jahn; Martin Klietz; Benjamin Krichevsky; Dirk O Stichtenoth; Felix Wedegärtner; Stefan Bleich; Helge Frieling; Johannes Heck
Journal:  J Neural Transm (Vienna)       Date:  2022-09-02       Impact factor: 3.850

Review 6.  Psychotic disorders in late life: a narrative review.

Authors:  Rajesh R Tampi; Juan Young; Rakin Hoq; Kyle Resnick; Deena J Tampi
Journal:  Ther Adv Psychopharmacol       Date:  2019-10-16
  6 in total

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