Literature DB >> 29529068

Correction: Gaussian decomposition of high-resolution melt curve derivatives for measuring genome-editing efficiency.

Michail Zaboikin, Carl Freter, Narasimhachar Srinivasakumar.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0190192.].

Year:  2018        PMID: 29529068      PMCID: PMC5846791          DOI: 10.1371/journal.pone.0194470

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


There is an error in the sentence preceding the fourth equation in the Materials and Methods section, under the subsection titled “Processing melt curve data”. The correct sentence and equation are: Efficiency of dsDNA detection at temperature x There is an error in the seventh equation in the Materials and Methods section. Please view the complete, correct equation here: There is an error in the fifth sentence of the second paragraph of the Results section under the subsection titled “Correction of RFU for temperature-dependent quenching of dsDNA-bound fluorophore”. The sentence “Two-Gaussian decomposition is superior to one-Gaussian modeling of derivative melt curves of unmodified target sites” should appear as a subheading.
  1 in total

1.  Gaussian decomposition of high-resolution melt curve derivatives for measuring genome-editing efficiency.

Authors:  Michail Zaboikin; Carl Freter; Narasimhachar Srinivasakumar
Journal:  PLoS One       Date:  2018-01-04       Impact factor: 3.240

  1 in total

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