| Literature DB >> 29528276 |
Marek A Mikulski1, Michael D Wichman2, Donald L Simmons3, Anthony N Pham1, Valentina Clottey1, Laurence J Fuortes1.
Abstract
Background Herbal formulations, traditional medicine, and complementary and alternative medicine are used by the majority of the world's population. Toxicity associated with use of Ayurvedic products due to metal content is an increasingly recognized potential public health problem. Objectives Report on toxic metals content of Ayurvedic products obtained during an investigation of lead poisoning among users of Ayurvedic medicine. Methods Samples of Ayurvedic formulations were analyzed for metals and metalloids following established US. Environmental Protection Agency methods. Results Lead was found in 65% of 252 Ayurvedic medicine samples with mercury and arsenic found in 38 and 32% of samples, respectively. Almost half of samples containing mercury, 36% of samples containing lead and 39% of samples containing arsenic had concentrations of those metals per pill that exceeded, up to several thousand times, the recommended daily intake values for pharmaceutical impurities. Conclusions Lack of regulations regarding manufacturing and content or purity of Ayurvedic and other herbal formulations poses a significant global public health problem.Entities:
Keywords: Toxic metals; ayurvedic medicine; complementary and alternative medicine; herbal formulations; public health response
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Year: 2018 PMID： 29528276 PMCID： PMC6060866 DOI： 10.1080/10773525.2018.1447880
Source DB: PubMed Journal: Int J Occup Environ Health ISSN： 1077-3525