Neta Solomon1, Ariel Many1, Rotem Orbach2, Dror Mandel2, Shiri Shinar1. 1. a Department of Obstetrics and Gynecology , Lis Maternity Hospital, Sourasky Medical Center , Tel Aviv , Israel. 2. b Department of Neonatology , Dana Dwek Children's Hospital , Tel Aviv , Israel.
Abstract
BACKGROUND: Hyponatremia during labor and delivery may result in severe maternal and neonatal sequelae. Our aim was to describe the direct effect of hyponatremia in labor on pregnancy outcome. METHODS: A case series of parturients diagnosed with hyponatremia during labor and their neonates. Clinical presentation, laboratory workup, and maternal and neonatal outcomes are presented. RESULTS: Four parturients and their corresponding six neonates were diagnosed with hyponatremia. Of these, two cases were caused by water intoxication and two were preeclampsia induced. While two were identified due to maternal or neonatal symptoms, two were diagnosed by routine laboratory testing. In all cases, low maternal sodium resulted in similarly low neonatal sodium. Neonatal symptoms included respiratory distress syndrome (RDS), lethargy, and jaundice. CONCLUSION: Psychogenic drinking during labor and preeclampsia may predispose to maternal hyponatremia, resulting in neonatal hyponatremia. Early recognition and treatment can prevent further maternal deterioration and adverse neonatal sequelae.
BACKGROUND:Hyponatremia during labor and delivery may result in severe maternal and neonatal sequelae. Our aim was to describe the direct effect of hyponatremia in labor on pregnancy outcome. METHODS: A case series of parturients diagnosed with hyponatremia during labor and their neonates. Clinical presentation, laboratory workup, and maternal and neonatal outcomes are presented. RESULTS: Four parturients and their corresponding six neonates were diagnosed with hyponatremia. Of these, two cases were caused by water intoxication and two were preeclampsia induced. While two were identified due to maternal or neonatal symptoms, two were diagnosed by routine laboratory testing. In all cases, low maternal sodium resulted in similarly low neonatal sodium. Neonatal symptoms included respiratory distress syndrome (RDS), lethargy, and jaundice. CONCLUSION: Psychogenic drinking during labor and preeclampsia may predispose to maternal hyponatremia, resulting in neonatal hyponatremia. Early recognition and treatment can prevent further maternal deterioration and adverse neonatal sequelae.
Entities:
Keywords:
Antidiuretic hormone (ADH); SIADH; hyponatremia; preeclampsia; water intoxication
Authors: Nilofar Dorani; Miranda M Zhang; Gopala K Rangan; Lara Abu-Zarour; Ho Ching Lau; Alexandra Munt; Ashley N Chandra; Sayanthooran Saravanabavan; Anna Rangan; Jennifer Q J Zhang; Martin Howell; Annette Ty Wong Journal: BMJ Open Date: 2021-12-09 Impact factor: 2.692