Literature DB >> 29525762

Lactate gap as a tool in identifying ethylene glycol poisoning.

A S Sagar1, Carlos A Jimenez2, Brandy J Mckelvy1.   

Abstract

Ethylene glycol toxicity is a known cause of anion gap metabolic acidosis, with the presence of an osmolar gap and the right clinical context suggesting to the diagnosis. Rapid recognition and early treatment is crucial. Unfortunately, ethylene glycol levels are not readily available and must be performed at a reference laboratory. We present a case where recognising the significance of the 'lactate gap' assisted in identifying ethylene glycol poisoning. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  adult intensive care; poisoning

Mesh：

Substances：

Year:  2018        PMID： 29525762      PMCID： PMC5848000          DOI： 10.1136/bcr-2018-224243

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  9 in total

1.  Artifactual elevation of measured plasma L-lactate concentration in the presence of glycolate.

Authors:  T J Morgan; C Clark; A Clague
Journal:  Crit Care Med       Date:  1999-10       Impact factor: 7.598

2.  Serum osmolality gap in postoperative patients in intensive care.

Authors:  H Inaba; H Hirasawa; T Mizuguchi
Journal:  Lancet       Date:  1987-06-13       Impact factor: 79.321

Review 3.  Toxic Alcohols.

Authors:  Jeffrey A Kraut; Michael E Mullins
Journal:  N Engl J Med       Date:  2018-01-18       Impact factor: 91.245

4.  American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee.

Authors:  D G Barceloux; E P Krenzelok; K Olson; W Watson
Journal:  J Toxicol Clin Toxicol       Date:  1999

Review 5.  Clinical toxicologic implications of ethylene glycol and glycolic acid poisoning.

Authors:  Albert D Fraser
Journal:  Ther Drug Monit       Date:  2002-04       Impact factor: 3.681

6.  Increased osmolal gap in alcoholic acidosis.

Authors:  G L Braden; C H Strayhorn; M J Germain; J G Mulhern; C L Skutches
Journal:  Arch Intern Med       Date:  1993-10-25

7.  Elevated lactate in ethylene glycol poisoning: True or false?

Authors:  Qing H Meng; Khosrow Adeli; Gordon A Zello; William H Porter; John Krahn
Journal:  Clin Chim Acta       Date:  2010-01-20       Impact factor: 3.786

8.  Relationship between serum glycolate and falsely elevated lactate in severe ethylene glycol poisoning.

Authors:  Alex F Manini; Robert S Hoffman; Kenneth E McMartin; Lewis S Nelson
Journal:  J Anal Toxicol       Date:  2009-04       Impact factor: 3.367

9.  Ethylene glycol poisoning presenting with a falsely elevated lactate level.

Authors:  Sandra Verelst; Pieter Vermeersch; Koen Desmet
Journal:  Clin Toxicol (Phila)       Date:  2009-03       Impact factor: 4.467
  9 in total
  2 in total

1.  Anion gap-opening metabolic acidosis and urinary findings in the early diagnosis of ethylene glycol poisoning: A case report.

Authors:  Kentaro Ukita; Kanako Otomune; Ryo Fujimoto; Kanako Hasegawa; Koichi Izumikawa; Nobutoshi Morimoto; Kazuhiro Sasaki; Akihito Hirasaki; Koichi Takaguchi
Journal:  Clin Case Rep       Date:  2022-01-07

2.  Mortality and associated risk factors in patients with severe methanol or ethylene glycol poisoning treated with dialysis: a retrospective cohort study.

Authors:  Emma Kuusela; Mikko J Järvisalo; Tapio Hellman; Panu Uusalo
Journal:  J Int Med Res       Date:  2022-02       Impact factor: 1.671
  2 in total

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