Literature DB >> 29525760

Pancytopenia: a rare complication of Graves' disease.

Vishnu Vardhan Garla1, Sohail Abdul Salim1, Licy L Yanes-Cardozo1.   

Abstract

A 27-year-old male patient who presented to the emergency room with complaints of sweating, palpitations, heat intolerance, insomnia and weight loss for the last 3 months. His medical history was significant for hypertension. On examination, he was tachycardic, hypertensive, had tremors of the upper extremities and a smooth goitre with a thyroid bruit. Laboratory assessment revealed a suppressed thyroid-stimulating hormone, high free thyroxine and positive thyroid receptor antibodies. Complete blood count showed pancytopenia. As part of the work-up for pancytopenia, haptoglobin, ferritin, Coombs test, reticulocyte count hepatitis B and C antibodies were done, all of which were normal. Patient was started on methimazole, propranolol and hydrocortisone. His symptoms improved through the hospital course and he was subsequently discharged. Thyroidectomy was done once the patient's hyperthyroidism was controlled. Levothyroxine was started for the control of postsurgical hypothyroidism. Six months after thyroidectomy, the patient was euthyroid and the pancytopenia resolved. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  malignant and benign haematology; thyroid disease

Mesh:

Substances:

Year:  2018        PMID: 29525760      PMCID: PMC5847973          DOI: 10.1136/bcr-2017-223887

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

1.  PANCYTOPENIA SECONDARY TO AUTOIMMUNE VITAMIN B12 DEFICIENCY IN GRAVES DISEASE.

Authors:  Vilmarie Rodriguez; Kristen M Gonzales; Anoop Mohamed Iqbal; Natasha Arbelo-Ramos; Kirk D Wyatt; Aida N Lteif; M Regina Castro
Journal:  AACE Clin Case Rep       Date:  2020-06-23

2.  Graves' Disease with Pancytopenia and Hepatic Dysfunction: A Rare Case Presentation.

Authors:  Kishore Kumar Behera; Kanhaiyalal Agrawal; Amit Kumar Adhya
Journal:  Indian J Nucl Med       Date:  2019 Jan-Mar

3.  A case of thyrotoxicosis-induced anemia in a patient with painless thyroiditis.

Authors:  Ichiro Komiya; Takeaki Tomoyose; Noriharu Yagi; Gen Ouchi; Tamio Wakugami
Journal:  Thyroid Res       Date:  2021-04-23

4.  Pre-treatment Neutropenia in Children and Adolescents with Autoimmune Hyperthyroidism

Authors:  Melissa Kaori S. Litao; Ana Gutierrez Alvarez; Bina Shah
Journal:  J Clin Res Pediatr Endocrinol       Date:  2020-12-02
  4 in total

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