Literature DB >> 29525484

The Cytokinin-Activating LOG-Family Proteins Are Not Lysine Decarboxylases.

Muhammad Naseem1, Elena Bencurova2, Thomas Dandekar3.   

Abstract

A conserved PGGxGTxxE motif misleads the cytokinin (CK) converting LONELY GUY enzymes to be wrongly annotated as lysine decarboxylases (LDCs). However, so far PGGxGTxxE motif-containing LDCs do not show any LDC activity. Instead, they show phosphoribohydrolase activity by converting inactive CK nucleotides into active free-base forms to invoke CK responses.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  LOG-family proteins; PGGxGTxxE motif; active cytokinins; cross-kingdom regulation; lysine decarboxylase; phosphoribohydrolase

Mesh：

Substances：

Year:  2018        PMID： 29525484     DOI： 10.1016/j.tibs.2018.01.002

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  5 in total

1.  Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system.

Authors:  Le Yu; Wenting Zhou; Yixuan She; Hongmin Ma; You-Sheng Cai; Ming Jiang; Zixin Deng; Neil P J Price; Wenqing Chen
Journal:  Nat Commun       Date:  2021-11-17       Impact factor: 14.919

Review 2.  Cytokinins: Wide-Spread Signaling Hormones from Plants to Humans with High Medical Potential.

Authors:  Moustafa Fathy; Sahar M Saad Eldin; Muhammad Naseem; Thomas Dandekar; Eman M Othman
Journal:  Nutrients       Date:  2022-04-02       Impact factor: 5.717

3.  Integrated structural and functional analysis of the protective effects of kinetin against oxidative stress in mammalian cellular systems.

Authors:  Muhammad Naseem; Eman M Othman; Moustafa Fathy; Jibran Iqbal; Fares M Howari; Fatima A AlRemeithi; Geema Kodandaraman; Helga Stopper; Elena Bencurova; Dimitrios Vlachakis; Thomas Dandekar
Journal:  Sci Rep       Date:  2020-08-07       Impact factor: 4.379

4.  A LONELY GUY protein of Bordetella pertussis with unique features is related to oxidative stress.

Authors:  Filippo Moramarco; Alfredo Pezzicoli; Laura Salvini; Rosanna Leuzzi; Werner Pansegrau; Enrico Balducci
Journal:  Sci Rep       Date:  2019-11-19       Impact factor: 4.379

Review 5.  The LONELY GUY gene family: from mosses to wheat, the key to the formation of active cytokinins in plants.

Authors:  Lei Chen; Geoffrey B Jameson; Yichu Guo; Jiancheng Song; Paula E Jameson
Journal:  Plant Biotechnol J       Date:  2022-03-01       Impact factor: 9.803
  5 in total

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