Literature DB >> 29525356

Looking back on the alternative complement pathway.

Peter J Lachmann1.   

Abstract

The alternative pathway of complement originated from the Properdin pathway originally described by the Pillemer laboratory in the 1950s. This work generated great controversy and it took several decades for a consensus on its components, its reaction sequence and its functions to emerge. This paper reviews this history and attempts to clarify some of the ambiguities that remain.
Copyright © 2018 Elsevier GmbH. All rights reserved.

Keywords:  Alternative pathway; Complement; Properdin

Mesh：

Substances：

Year:  2018        PMID： 29525356     DOI： 10.1016/j.imbio.2018.02.001

Source DB:  PubMed          Journal:  Immunobiology        ISSN： 0171-2985            Impact factor:   3.144


  12 in total

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