A L Tatu1, L C Nwabudike2. 1. Medical and Pharmaceutical Research Unit/Competitive, Interdisciplinary Research Integrated Platform 'Dunărea de Jos', ReForm-UDJG, Department of Dermatology, Faculty of Medicine and Pharmacy/Pharmacology Sciences Department, 'Dunărea de Jos' University of Galati, Al.I.Cuza street no 39, Galati, 800101, Romania. 2. N. Paulescu Institute of Diabetes, 5-7 Ion Movila street, Sect 2, Bucharest, 70000, Romania.