Maha A Bahammam1. 1. Department of Periodontology, Faculty of Dentistry, King Abdulaziz University, P. O. Box 80209, Jeddah, 21589, Kingdom of Saudi Arabia. mbahammam@kau.edu.sa.
Abstract
OBJECTIVE: This prospective randomized clinical trial was conducted to determine whether the application of a platelet-rich fibrin (PRF) palatal bandage after harvesting free gingival grafts (FGG) would improve healing of donor sites and decrease pain scores and patient discomfort. MATERIALS AND METHODS: Twenty-four patients received FGG to augment keratinized tissue dimensions. The application of a PRF bandage was decided randomly (n = 12 in each group). Patients reported their pain levels for the first 7 days of healing using the visual analog scale (VAS), 101-point numerical rating scale (NRS-101), and 4-point verbal rating scale (VRS-4). The patients' pre-operative anxiety levels were measured using three anxiety scales. The healing of the donor sites was evaluated and compared to preoperative records. Data were assessed and recorded before surgery and at 1, 2, 3, 4, and 8 weeks postoperatively. RESULTS:Dental anxiety and state-trait anxiety were evaluated at baseline and correlated to the postoperative pain scores. There were no significant differences in anxiety levels between the two groups; yet, they could potentially influence the outcome of any surgery and were included as covariates. The patients in the PRF group reported significantly lower pain scores and their pain levels returned to baseline levels earlier, compared to the control group. CONCLUSIONS:PRF palatal bandages significantly reduced postoperative pain and discomfort and facilitated wound healing after harvesting FGG. CLINICAL RELEVANCE: The study provided evaluation of patient-centered outcomes, which is timely, significant, and could benefit both periodontists and patients.
RCT Entities:
OBJECTIVE: This prospective randomized clinical trial was conducted to determine whether the application of a platelet-rich fibrin (PRF) palatal bandage after harvesting free gingival grafts (FGG) would improve healing of donor sites and decrease pain scores and patient discomfort. MATERIALS AND METHODS: Twenty-four patients received FGG to augment keratinized tissue dimensions. The application of a PRF bandage was decided randomly (n = 12 in each group). Patients reported their pain levels for the first 7 days of healing using the visual analog scale (VAS), 101-point numerical rating scale (NRS-101), and 4-point verbal rating scale (VRS-4). The patients' pre-operative anxiety levels were measured using three anxiety scales. The healing of the donor sites was evaluated and compared to preoperative records. Data were assessed and recorded before surgery and at 1, 2, 3, 4, and 8 weeks postoperatively. RESULTS: Dental anxiety and state-trait anxiety were evaluated at baseline and correlated to the postoperative pain scores. There were no significant differences in anxiety levels between the two groups; yet, they could potentially influence the outcome of any surgery and were included as covariates. The patients in the PRF group reported significantly lower pain scores and their pain levels returned to baseline levels earlier, compared to the control group. CONCLUSIONS: PRF palatal bandages significantly reduced postoperative pain and discomfort and facilitated wound healing after harvesting FGG. CLINICAL RELEVANCE: The study provided evaluation of patient-centered outcomes, which is timely, significant, and could benefit both periodontists and patients.
Authors: Joseph Choukroun; Antoine Diss; Alain Simonpieri; Marie-Odile Girard; Christian Schoeffler; Steve L Dohan; Anthony J J Dohan; Jaafar Mouhyi; David M Dohan Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Date: 2006-03