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Literature DB >> 2952064

In vitro activity of a new macrolide, A-56268, compared with that of roxithromycin, erythromycin, and clindamycin.

Abstract

A new macrolide (A-56268) was found to be approximately twice as active as erythromycin and four to eight times more active than roxithromycin. All three macrolides were similar in their potency against anaerobes. Human plasma enhanced the antistaphylococcal activity of A-56268 and erythromycin but reduced the activities of roxithromycin and clindamycin.

Entities: Chemical Species

Mesh：

Substances：

Year: 1987 PMID： 2952064 PMCID： PMC174723 DOI： 10.1128/AAC.31.2.343

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

9 in total

1. In vitro activity of rosamicin, josamycin, erythromycin, and clindamycin against beta-lactamase-nagative and beta-lactamase-positive strains of Neisseria gonorrhoeae.

Authors: J W Biddle; C Thornsberry
Journal: Antimicrob Agents Chemother Date: 1979-02 Impact factor: 5.191

2. In vitro comparison of the activity of RU 28965, a new macrolide, with that of erythromycin against aerobic and anaerobic bacteria.

Authors: T Barlam; H C Neu
Journal: Antimicrob Agents Chemother Date: 1984-04 Impact factor: 5.191

3. Erythromycin: a microbial and clinical perspective after 30 years of clinical use (1).

Authors: J A Washington; W R Wilson
Journal: Mayo Clin Proc Date: 1985-03 Impact factor: 7.616

4. In vitro evaluation of three new macrolide antimicrobial agents, RU28965, RU29065, and RU29702, and comparisons with other orally administered drugs.

Authors: R N Jones; A L Barry; C Thornsberry
Journal: Antimicrob Agents Chemother Date: 1983-08 Impact factor: 5.191

5. Aerobically incubated thioglycolate broth disk method for antibiotic susceptibility testing of anaerobes.

Authors: T A Kurzynski; J W Yrios; A G Helstad; C R Field
Journal: Antimicrob Agents Chemother Date: 1976-10 Impact factor: 5.191

6. Effect of carbon dioxide and pH on susceptibility of Bacteroides fragilis group to erythromycin.

Authors: S L Hansen; P Swomley; G Drusano
Journal: Antimicrob Agents Chemother Date: 1981-02 Impact factor: 5.191

7. In vitro activity of the new macrolide antibiotic roxithromycin (RU 28965) against clinical isolates of Haemophilus influenzae.

Authors: J H Jorgensen; J S Redding; A W Howell
Journal: Antimicrob Agents Chemother Date: 1986-05 Impact factor: 5.191

8. Effect of several components of anaerobic incubation on antibiotic susceptibility test results.

Authors: J E Rosenblatt; F Schoenknecht
Journal: Antimicrob Agents Chemother Date: 1972-05 Impact factor: 5.191

9. In vitro and in vivo evaluation of A-56268 (TE-031), a new macrolide.

Authors: P B Fernandes; R Bailer; R Swanson; C W Hanson; E McDonald; N Ramer; D Hardy; N Shipkowitz; R R Bower; E Gade
Journal: Antimicrob Agents Chemother Date: 1986-12 Impact factor: 5.191

9 in total

17 in total

Review 1. Treatment of abnormal vaginal flora in early pregnancy with clindamycin for the prevention of spontaneous preterm birth: a systematic review and metaanalysis.

Authors: Ronald F Lamont; Chia-Ling Nhan-Chang; Jack D Sobel; Kimberly Workowski; Agustin Conde-Agudelo; Roberto Romero
Journal: Am J Obstet Gynecol Date: 2011-04-02 Impact factor: 8.661

Review 2. New directions for macrolide antibiotics: structural modifications and in vitro activity.

Authors: H A Kirst; G D Sides
Journal: Antimicrob Agents Chemother Date: 1989-09 Impact factor: 5.191

3. Design and formulation technique of a novel drug delivery system for azithromycin and its anti-bacterial activity against Staphylococcus aureus.

Authors: M Joyce Nirmala; Amitava Mukherjee; N Chandrasekaran
Journal: AAPS PharmSciTech Date: 2013-06-26 Impact factor: 3.246

4. Comparative in vitro activity of the new macrolide A-56268 against anaerobic bacteria.

Authors: H M Wexler; S M Finegold
Journal: Eur J Clin Microbiol Date: 1987-08 Impact factor: 3.267

Review 5. World-wide development of antibiotic resistance in pneumococci.

Authors: P C Appelbaum
Journal: Eur J Clin Microbiol Date: 1987-08 Impact factor: 3.267

Review 6. Azithromycin. A review of its pharmacological properties and use as 3-day therapy in respiratory tract infections.

Authors: C J Dunn; L B Barradell
Journal: Drugs Date: 1996-03 Impact factor: 9.546

7. In vitro activities of azithromycin (CP 62,993), clarithromycin (A-56268; TE-031), erythromycin, roxithromycin, and clindamycin.

Authors: A L Barry; R N Jones; C Thornsberry
Journal: Antimicrob Agents Chemother Date: 1988-05 Impact factor: 5.191