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Literature DB >> 29520421

Regulatory functions of γδ T cells.

Christian Peters¹, Dieter Kabelitz¹, Daniela Wesch².

Abstract

γδ T cells share characteristics of innate and adaptive immune cells and are involved in a broad spectrum of pro-inflammatory functions. Nonetheless, there is accumulating evidence that γδ T cells also exhibit regulatory functions. In this review, we describe the different phenotypes of regulatory γδ T cells in correlation with the identified mechanisms of suppression.

Keywords: Adenosine; Checkpoint; FoxP3; Gammadelta; IL-10; Suppressive; T Lymphocytes; TGF-β

Mesh：

Substances：

Year: 2018 PMID： 29520421 DOI： 10.1007/s00018-018-2788-x

Source DB: PubMed Journal: Cell Mol Life Sci ISSN： 1420-682X Impact factor: 9.261

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