Literature DB >> 29520335

The mechanistic implications of gene expression studies in SSc: Insights from Systems Biology.

Jaclyn N Taroni1, J Matthew Mahoney2, Michael L Whitfield1,3.   

Abstract

Entities:  

Keywords:  Biomarkers; data integration; gene expression; genomics; macrophages; networks; scleroderma; systemic sclerosis

Year:  2017        PMID： 29520335      PMCID： PMC5837066          DOI： 10.1007/s40674-017-0072-0

Source DB:  PubMed          Journal:  Curr Treatm Opt Rheumatol        ISSN： 2198-6002


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  43 in total

Review 1.  Mycophenolate mofetil and its mechanisms of action.

Authors:  A C Allison; E M Eugui
Journal:  Immunopharmacology       Date:  2000-05

2.  A four-gene biomarker predicts skin disease in patients with diffuse cutaneous systemic sclerosis.

Authors:  G Farina; D Lafyatis; R Lemaire; R Lafyatis
Journal:  Arthritis Rheum       Date:  2010-02

3.  A Functional Genomic Meta-Analysis of Clinical Trials in Systemic Sclerosis: Toward Precision Medicine and Combination Therapy.

Authors:  Jaclyn N Taroni; Viktor Martyanov; J Matthew Mahoney; Michael L Whitfield
Journal:  J Invest Dermatol       Date:  2016-12-21       Impact factor: 8.551

4.  Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients.

Authors:  Lisa M Rice; Cristina M Padilla; Sarah R McLaughlin; Allison Mathes; Jessica Ziemek; Salma Goummih; Sashidhar Nakerakanti; Michael York; Giuseppina Farina; Michael L Whitfield; Robert F Spiera; Romy B Christmann; Jessica K Gordon; Janice Weinberg; Robert W Simms; Robert Lafyatis
Journal:  J Clin Invest       Date:  2015-06-22       Impact factor: 14.808

Review 5.  Molecular stratification and precision medicine in systemic sclerosis from genomic and proteomic data.

Authors:  Viktor Martyanov; Michael L Whitfield
Journal:  Curr Opin Rheumatol       Date:  2016-01       Impact factor: 5.006

6.  Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients.

Authors:  Chris Cheadle; Alan E Berger; Stephen C Mathai; Dmitry N Grigoryev; Tonya N Watkins; Yumiko Sugawara; Sangjucta Barkataki; Jinshui Fan; Meher Boorgula; Laura Hummers; Ari L Zaiman; Reda Girgis; Michael A McDevitt; Roger A Johns; Frederick Wigley; Kathleen C Barnes; Paul M Hassoun
Journal:  PLoS One       Date:  2012-04-24       Impact factor: 3.240

7.  Evolution of complex modular biological networks.

Authors:  Arend Hintze; Christoph Adami
Journal:  PLoS Comput Biol       Date:  2008-02       Impact factor: 4.475

8.  Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures.

Authors:  Jaclyn N Taroni; Viktor Martyanov; Chiang-Ching Huang; J Matthew Mahoney; Ikuo Hirano; Brandon Shetuni; Guang-Yu Yang; Darren Brenner; Barbara Jung; Tammara A Wood; Swati Bhattacharyya; Orit Almagor; Jungwha Lee; Arlene Sirajuddin; John Varga; Rowland W Chang; Michael L Whitfield; Monique Hinchcliff
Journal:  Arthritis Res Ther       Date:  2015-07-29       Impact factor: 5.156

9.  Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma.

Authors:  Elizabeth E Gerber; Elena M Gallo; Stefani C Fontana; Elaine C Davis; Fredrick M Wigley; David L Huso; Harry C Dietz
Journal:  Nature       Date:  2013-10-09       Impact factor: 49.962

10.  Understanding multicellular function and disease with human tissue-specific networks.

Authors:  Casey S Greene; Arjun Krishnan; Aaron K Wong; Emanuela Ricciotti; Rene A Zelaya; Daniel S Himmelstein; Ran Zhang; Boris M Hartmann; Elena Zaslavsky; Stuart C Sealfon; Daniel I Chasman; Garret A FitzGerald; Kara Dolinski; Tilo Grosser; Olga G Troyanskaya
Journal:  Nat Genet       Date:  2015-04-27       Impact factor: 38.330
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  2 in total

Review 1.  Big data in systemic sclerosis: Great potential for the future.

Authors:  Mislav Radic; Tracy M Frech
Journal:  J Scleroderma Relat Disord       Date:  2020-07-06

2.  Regulator combinations identify systemic sclerosis patients with more severe disease.

Authors:  Yue Wang; Jennifer M Franks; Monica Yang; Diana M Toledo; Tammara A Wood; Monique Hinchcliff; Michael L Whitfield
Journal:  JCI Insight       Date:  2020-09-03
  2 in total

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