Literature DB >> 29519878

Posterior scleral reinforcement using genipin-cross-linked sclera for macular hole retinal detachment in highly myopic eyes.

Shuang-Qian Zhu1, An-Peng Pan1, Lin-Yan Zheng1, Yue Wu1, An-Quan Xue1.   

Abstract

BACKGROUND/AIMS: To investigate the surgical outcomes of posterior scleral reinforcement (PSR) using genipin-cross-linked sclera to treat macular hole retinal detachment (MHRD) in highly myopic eyes.
METHODS: Nineteen patients with high myopia (19 eyes) with MHRD were treated sequentially with genipin-cross-linked PSR and were followed at least for 1 year after the surgery. The best corrected visual acuity (BCVA), axial length (AL), optical coherence tomography (OCT) outcomes and the complications were evaluated.
RESULTS: Macular hole was closed in 73.7% of the eyes, foveal reattachment rate was 100%. The mean logMAR BCVA improved from 1.27±0.55 preoperatively to 0.88±0.55 postoperatively. The preoperative AL (29.88±1.97 mm) was decreased (27.73±1.84 mm) after the operation (p<0.001).
CONCLUSIONS: For at least a 1-year period of follow-up, PSR with genipin-cross-linked sclera should be considered as a preferred surgical approach to treat MHRD in highly myopic eyes, especially when foveal retinoschisis is also documented. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  macula; retina; treatment surgery

Mesh:

Substances:

Year:  2018        PMID: 29519878     DOI: 10.1136/bjophthalmol-2017-311340

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  2 in total

1.  Biomechanical Considerations of Patching Material for Posterior Scleral Reinforcement Surgery.

Authors:  Jinlei Ma; Fangyuan Wu; Zhiyong Liu; Yijiong Fang; Xu Chu; Linyan Zheng; Anquan Xue; Kaihui Nan; Jia Qu; Lingyun Cheng
Journal:  Front Med (Lausanne)       Date:  2022-05-16

2.  Changes in Rat Scleral Collagen Structure Induced by UVA-Riboflavin Crosslinking at Various Tissue Depths in Whole Globe Versus Scleral Patch.

Authors:  Yuan Miao; Juan Liu; Sruti S Akella; Jessie Wang; Shaowei Li; Roy S Chuck; Cheng Zhang
Journal:  Transl Vis Sci Technol       Date:  2022-08-01       Impact factor: 3.048

  2 in total

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