Photo-responsive membrane surface: Switching from bactericidal to bacteria-resistant property.

In this paper, a photo-responsive bactericidal and bacteria-resistant membrane was successfully prepared via the integration of atom transfer radical polymerization (ATRP) and click chemistry. Azide-functionalized polycationic poly (N, N-dimethyl-N-(2-(methacryloyloxy)ethyl)-N-((2-nitrobenzyl)oxy)-2-oxoethanaminium bromide) (PDMAEMA-NBE) was synthesized by ATRP. Then, the PDMAEMA-NBE was clicked on alkynyl-functionalized polyethersulfone (PES) membrane surface, and proved by X-ray photoelectron spectrometer (XPS). Upon UV irradiation, the polycationic surface would switch to polyzwitterionic one. Before and after the irradiation, the zeta potentials of the surface altered from +14.7 to -3.8mV, and the water contact angle decreased from 64.0° to 52.7°. The polycationic surface exhibited excellent bactericidal property and the dead bacteria could detach from the polyzwitterionic surface induced by the subsequent UV irradiation. It demonstrated that the designing of photo-responsive membrane surface could be a new strategy for antibacterial adhesion.