| Literature DB >> 29519419 |
A Papadimitriou1, I Ketikidis2, M-E K Stathopoulou2, C N Banti3, C Papachristodoulou4, L Zoumpoulakis5, S Agathopoulos6, G V Vagenas7, S K Hadjikakou8.
Abstract
Curcumin (Curc) reacts with zinc di‑iodine (ZnI2) in 2:1molar ratio in the presence of an excess of a base triethylamine ((CH3CH2)3N) in methanol (CH3OH) solution towards the amorphous solid material of formula [ZnI2(Curc)2] (1). The complex was characterized by melting point (m.p.), Fourier Transform-Infra Red (FT-IR) and Nuclear Magnetic Resonance of hydrogen nucleus (1H NMR) spectroscopy. The formula of 1 was determined by X-ray fluorescence (XRF) analysis. The retention of the structure in solution was confirmed by 1H NMR spectroscopy. The antimicrobial activity of the complex has been studied against the bacteria Pseudomonas aeruginosa (PAO1). The Minimum Inhibitory Concentrations (MIC) of the compounds 1 and Curc against P. aeruginosa (PAO1) are: 71.3μΜ (75.3μg/mL) for [ZnI2(Curc)2] and 339μM (125μg/mL) for Curc, respectively. Moreover, the antimicrobial activity of the new material which was diffused in polystyrene against biofilm formed by PAO1 was also calculated.Entities:
Keywords: Active packaging materials; Antimicrobial materials; Biological inorganic chemistry; Curcumine; Pseudomonas aeruginosa
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Year: 2017 PMID： 29519419 DOI： 10.1016/j.msec.2017.11.041
Source DB: PubMed Journal: Mater Sci Eng C Mater Biol Appl ISSN： 0928-4931 Impact factor: 7.328