| Literature DB >> 29518360 |
Joe Udeochu1, Faten A Sayed2, Li Gan3.
Abstract
Mutations in TREM2 increase risk for late-onset AD. In this issue of Neuron, Zhao et al. (2018) show that TREM2 binds Aβ to enhance its clearance and Lee et al. (2018) demonstrate that human TREM2 expression in AD mice ameliorates Aβ-associated deficits.Entities:
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Year: 2018 PMID： 29518360 DOI： 10.1016/j.neuron.2018.02.018
Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173