Literature DB >> 29517027

A new era of rationally designed antipsychotics.

David R Sibley, Lei Shi.   

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Year:  2018        PMID： 29517027      PMCID： PMC6114090          DOI： 10.1038/d41586-018-02328-z

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  15 in total

Review 1.  Does fast dissociation from the dopamine d(2) receptor explain the action of atypical antipsychotics?: A new hypothesis.

Authors:  S Kapur; P Seeman
Journal:  Am J Psychiatry       Date:  2001-03       Impact factor: 18.112

Review 2.  Multiple receptors for dopamine.

Authors:  J W Kebabian; D B Calne
Journal:  Nature       Date:  1979-01-11       Impact factor: 49.962

Review 3.  Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds.

Authors:  Amy E Moritz; R Benjamin Free; David R Sibley
Journal:  Cell Signal       Date:  2017-07-14       Impact factor: 4.315

4.  Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.

Authors:  Ellen Y T Chien; Wei Liu; Qiang Zhao; Vsevolod Katritch; Gye Won Han; Michael A Hanson; Lei Shi; Amy Hauck Newman; Jonathan A Javitch; Vadim Cherezov; Raymond C Stevens
Journal:  Science       Date:  2010-11-19       Impact factor: 47.728

5.  Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs.

Authors:  I Creese; D R Burt; S H Snyder
Journal:  Science       Date:  1976-04-30       Impact factor: 47.728

Review 6.  Recent advances in the search for D3- and D4-selective drugs: probes, models and candidates.

Authors:  Stefan Löber; Harald Hübner; Nuska Tschammer; Peter Gmeiner
Journal:  Trends Pharmacol Sci       Date:  2011-01-12       Impact factor: 14.819

Review 7.  Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient.

Authors:  S Kapur; G Remington
Journal:  Biol Psychiatry       Date:  2001-12-01       Impact factor: 13.382

Review 8.  Beyond small-molecule SAR: using the dopamine D3 receptor crystal structure to guide drug design.

Authors:  Thomas M Keck; Caitlin Burzynski; Lei Shi; Amy Hauck Newman
Journal:  Adv Pharmacol       Date:  2014

9.  Ligand discovery from a dopamine D3 receptor homology model and crystal structure.

Authors:  Jens Carlsson; Ryan G Coleman; Vincent Setola; John J Irwin; Hao Fan; Avner Schlessinger; Andrej Sali; Bryan L Roth; Brian K Shoichet
Journal:  Nat Chem Biol       Date:  2011-09-18       Impact factor: 15.040

10.  Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors.

Authors:  David A Sykes; Holly Moore; Lisa Stott; Nicholas Holliday; Jonathan A Javitch; J Robert Lane; Steven J Charlton
Journal:  Nat Commun       Date:  2017-10-02       Impact factor: 14.919
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  1 in total

1.  Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism.

Authors:  J Robert Lane; Ara M Abramyan; Pramisha Adhikari; Alastair C Keen; Kuo-Hao Lee; Julie Sanchez; Ravi Kumar Verma; Herman D Lim; Hideaki Yano; Jonathan A Javitch; Lei Shi
Journal:  Elife       Date:  2020-01-27       Impact factor: 8.140
  1 in total

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