Johan Newell1, Olivier Mairesse2,3,4,5, Daniel Neu2,5. 1. Sleep Laboratory and Unit for Chronobiology U78, Brugmann University Hospital, Université Libre de Bruxelles (U.L.B.), Arthur Van Gehuchten Square 4, Building Hh, 1020, Brussels, Belgium. johan.newell@chu-brugmann.be. 2. Sleep Laboratory and Unit for Chronobiology U78, Brugmann University Hospital, Université Libre de Bruxelles (U.L.B.), Arthur Van Gehuchten Square 4, Building Hh, 1020, Brussels, Belgium. 3. Department EXTO, Vrije Universiteit Brussel (V.U.B.), Brussels, Belgium. 4. Department LIFE, Royal Military Academy, Brussels, Belgium. 5. UNI Neuroscience Institute, ULB 312 Faculty of Medicine and ULB 388 FMS, Université Libre de Bruxelles (U.L.B.), Brussels, Belgium.
Abstract
PURPOSE: Until now, there is no clear consensus on optimal care for mild sleep-related breathing disorders (SRBD) in general or for positional obstructive sleep apnea (POSA) in particular. Most proposed treatment options are either invasive and/or expensive. Positional therapy (PT) may therefore present as a valuable first-line intervention in POSA. METHODS: Twenty-eight patients presenting with POSA were enrolled in a prospective cohort study. The protocol consisted of three nights of polysomnography (PSG) in an academic sleep lab. Inclusion was based on the first PSG. During a consecutive PSG, PT was provided by means of a sleep-positioning pillow (Posiform®). The third PSG was performed after 1 month of PT. Sleepiness, fatigue, and sleep quality were assessed with the Epworth Sleepiness Scale (ESS), the fatigue severity scale (FSS), the Pittsburgh Sleep Quality Index (PSQI), and the Function Outcomes of Sleep Questionnaire (FOSQ) at baseline, and after 1 and at 6 months of PT alongside satisfaction and compliance ratings. RESULTS: Significant immediate treatment effects after one night and sustained after 1 month were observed by significant reductions of sleep in supine position (p < .001), sleep fragmentation (p < .05), apnea-hypopnea (p < .001), respiratory disturbance (p < .001), and oxygen desaturation (p < .001) indices. PSQI (p < .001), ESS (p < .005), and FOSQ (p < .001) also showed significant and persistent improvements. CONCLUSIONS: Combined effects on sleep-related respiration and clinical symptoms were observed after PT initiation as well as after 1 month using the sleep-positioning pillow. Furthermore, reported compliance and overall satisfaction appeared to be highly concordant both at 1 month and 6 months follow-up.
PURPOSE: Until now, there is no clear consensus on optimal care for mild sleep-related breathing disorders (SRBD) in general or for positional obstructive sleep apnea (POSA) in particular. Most proposed treatment options are either invasive and/or expensive. Positional therapy (PT) may therefore present as a valuable first-line intervention in POSA. METHODS: Twenty-eight patients presenting with POSA were enrolled in a prospective cohort study. The protocol consisted of three nights of polysomnography (PSG) in an academic sleep lab. Inclusion was based on the first PSG. During a consecutive PSG, PT was provided by means of a sleep-positioning pillow (Posiform®). The third PSG was performed after 1 month of PT. Sleepiness, fatigue, and sleep quality were assessed with the Epworth Sleepiness Scale (ESS), the fatigue severity scale (FSS), the Pittsburgh Sleep Quality Index (PSQI), and the Function Outcomes of Sleep Questionnaire (FOSQ) at baseline, and after 1 and at 6 months of PT alongside satisfaction and compliance ratings. RESULTS: Significant immediate treatment effects after one night and sustained after 1 month were observed by significant reductions of sleep in supine position (p < .001), sleep fragmentation (p < .05), apnea-hypopnea (p < .001), respiratory disturbance (p < .001), and oxygen desaturation (p < .001) indices. PSQI (p < .001), ESS (p < .005), and FOSQ (p < .001) also showed significant and persistent improvements. CONCLUSIONS: Combined effects on sleep-related respiration and clinical symptoms were observed after PT initiation as well as after 1 month using the sleep-positioning pillow. Furthermore, reported compliance and overall satisfaction appeared to be highly concordant both at 1 month and 6 months follow-up.
Authors: J Peter van Maanen; Wietske Richard; Ellen R Van Kesteren; Madeline J L Ravesloot; D Martin Laman; Antonius A J Hilgevoord; Nico de Vries Journal: J Sleep Res Date: 2011-10-22 Impact factor: 3.981
Authors: Raphael C Heinzer; Cyril Pellaton; Vincianne Rey; Andrea O Rossetti; Gianpaolo Lecciso; José Haba-Rubio; Mehdi Tafti; Gilles Lavigne Journal: Sleep Med Date: 2012-01-18 Impact factor: 3.492
Authors: James J Bignold; Jeremy D Mercer; Nick A Antic; R Doug McEvoy; Peter G Catcheside Journal: J Clin Sleep Med Date: 2011-08-15 Impact factor: 4.062
Authors: Vasileios T Stavrou; Yiannis Koutedakis; Kyriaki Astara; George D Vavougios; Eirini Papayianni; Ilias T Stavrou; Fotini Bardaka; Chaido Pastaka; Konstantinos I Gourgoulianis Journal: Front Med (Lausanne) Date: 2022-03-09