Literature DB >> 29513064

Contribution of intratympanic steroids in the primary treatment of sudden hearing loss.

Hasan Demirhan1, Ali Rıza Gökduman1, Bahtiyar Hamit1, Müge Fethiye Yürekli Altındağ1, Özgür Yiğit1.   

Abstract

OBJECTIVE: The primary objective is to investigate the contribution of intratympanic steroids in the primary treatment of idiopathic sudden sensorineural hearing loss (ISSNHL). The secondary objective is to compare methylprednisolone (MP) and dexamethasone in terms of their effectiveness and injection-site pain.
METHODS: Two hundred and four patients with ISSNHL, 144 patients underwent systemic steroid therapy (SST) alone and 60 patients underwent combined therapy (CT). The effectiveness of the treatment was assessed according to the Furuhashi criteria. Injection-site pain after the procedure was assessed at 5 and 60 min on a visual analog scale (VAS).
RESULTS: Successful recovery was 55% in the CT group and 34% in the SST alone group (p = .004). Patients whose initial hearing level is severe, the success rate was statistically significantly higher with CT (p = .0001). Hearing improvement differed significantly between the MP and dexamethasone (p = .015). Injection-site pain at 5 min after the procedure, higher VAS scores were obtained with MP (p = .002).
CONCLUSION: In the primary treatment of sudden hearing loss, in which the level of hearing loss is 70-89 dB HL, the addition of ITS to the treatment significantly increased the success rate. The pain occurring in the middle ear was high but tolerable in the first few minutes by MP.

Entities:  

Keywords:  Hearing loss; dexamethasone; injection; intratympanic; methylprednisolone; sudden; visual analog scale

Mesh:

Substances:

Year:  2018        PMID: 29513064     DOI: 10.1080/00016489.2018.1438660

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  3 in total

Review 1.  Clinical management and progress in sudden sensorineural hearing loss during pregnancy.

Authors:  Shaobing Xie; Xuewen Wu
Journal:  J Int Med Res       Date:  2019-08-27       Impact factor: 1.671

2.  Combination of Pulse Steroid with Intratympanic Injections in Sudden Sensorineural Hearing Loss.

Authors:  Maryam Amizadeh; Keramat Mozafarnia; Javad Moslemikia; Ahmad Naghibzadeh-Tahami
Journal:  Iran J Otorhinolaryngol       Date:  2021-01

3.  [Tolerance and acceptance of intratympanic injections].

Authors:  Guido Mühlmeier; Matthias Tisch
Journal:  HNO       Date:  2022-08-02       Impact factor: 1.330

  3 in total

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