Literature DB >> 29513044

Pain chronification: what should a non-pain medicine specialist know?

Bart Morlion1, Flaminia Coluzzi2, Dominic Aldington3, Magdalena Kocot-Kepska4, Joseph Pergolizzi5, Ana Cristina Mangas6, Karsten Ahlbeck7, Eija Kalso8.   

Abstract

OBJECTIVE: Pain is one of the most common reasons for an individual to consult their primary care physician, with most chronic pain being treated in the primary care setting. However, many primary care physicians/non-pain medicine specialists lack enough awareness, education and skills to manage pain patients appropriately, and there is currently no clear, common consensus/formal definition of "pain chronification".
METHODS: This article, based on an international Change Pain Chronic Advisory Board meeting which was held in Wiesbaden, Germany, in October 2016, provides primary care physicians/non-pain medicine specialists with a narrative overview of pain chronification, including underlying physiological and psychosocial processes, predictive factors for pain chronification, a brief summary of preventive strategies, and the role of primary care physicians and non-pain medicine specialists in the holistic management of pain chronification.
RESULTS: Based on currently available evidence, we propose the following consensus-based definition of pain chronification which provides a common framework to raise awareness among non-pain medicine specialists: "Pain chronification describes the process of transient pain progressing into persistent pain; pain processing changes as a result of an imbalance between pain amplification and pain inhibition; genetic, environmental and biopsychosocial factors determine the risk, the degree, and time-course of chronification."
CONCLUSIONS: Early intervention plays an important role in preventing pain chronification and, as key influencers in the management of patients with acute pain, it is critical that primary care physicians are equipped with the necessary awareness, education and skills to manage pain patients appropriately.

Entities:  

Keywords:  Chronic pain; chronification; non-pain medicine specialist; pain

Mesh:

Year:  2018        PMID: 29513044     DOI: 10.1080/03007995.2018.1449738

Source DB:  PubMed          Journal:  Curr Med Res Opin        ISSN: 0300-7995            Impact factor:   2.580


  14 in total

1.  Dual-Acting Peripherally Restricted Delta/Kappa Opioid (CAV1001) Produces Antinociception in Animal Models of Sub-Acute and Chronic Pain.

Authors:  Craig T Hartrick; Dominic Poulin; Rebekka Molenaar; Allison Hartrick
Journal:  J Pain Res       Date:  2020-10-06       Impact factor: 3.133

Review 2.  Assessing and Treating Chronic Pain in Patients with End-Stage Renal Disease.

Authors:  Flaminia Coluzzi
Journal:  Drugs       Date:  2018-09       Impact factor: 9.546

Review 3.  Left to themselves: Time to target chronic pain in childhood rare diseases.

Authors:  Christine B Sieberg; Alyssa Lebel; Erin Silliman; Scott Holmes; David Borsook; Igor Elman
Journal:  Neurosci Biobehav Rev       Date:  2021-03-24       Impact factor: 8.989

Review 4.  Pharmacological rationale for tapentadol therapy: a review of new evidence.

Authors:  Patrizia Romualdi; Mariagrazia Grilli; Pier Luigi Canonico; Massimo Collino; Anthony H Dickenson
Journal:  J Pain Res       Date:  2019-05-16       Impact factor: 3.133

Review 5.  Tapentadol: an effective option for the treatment of back pain.

Authors:  Flaminia Coluzzi; Enrico Polati; Ulderico Freo; Mariagrazia Grilli
Journal:  J Pain Res       Date:  2019-05-16       Impact factor: 3.133

Review 6.  Tapentadol in the treatment of osteoarthritis: pharmacological rationale and clinical evidence.

Authors:  Giuseppe Rinonapoli; Stefano Coaccioli; Lorenzo Panella
Journal:  J Pain Res       Date:  2019-05-16       Impact factor: 3.133

Review 7.  Why Unidimensional Pain Measurement Prevails in the Pediatric Acute Pain Context and What Multidimensional Self-Report Methods Can Offer.

Authors:  Tiina Jaaniste; Melanie Noel; Renee D Yee; Joseph Bang; Aidan Christopher Tan; G David Champion
Journal:  Children (Basel)       Date:  2019-12-02

8.  Antinociceptive Effect of Lodenafil Carbonate in Rodent Models of Inflammatory Pain and Spinal Nerve Ligation-Induced Neuropathic Pain.

Authors:  Marcio Carneiro Vieira; Fernanda Bezerra de Mello Monte; Bruno Eduardo Dematte; Tadeu Lima Montagnoli; Guilherme Carneiro Montes; Jaqueline Soares da Silva; Rosalia Mendez-Otero; Margarete Manhães Trachez; Roberto Takashi Sudo; Gisele Zapata-Sudo
Journal:  J Pain Res       Date:  2021-03-30       Impact factor: 3.133

9.  The Feasibility and Effectiveness of a New Practical Multidisciplinary Treatment for Low-Back Pain: A Randomized Controlled Trial.

Authors:  Pia-Maria Wippert; David Drießlein; Heidrun Beck; Christian Schneider; Anne-Katrin Puschmann; Winfried Banzer; Marcus Schiltenwolf
Journal:  J Clin Med       Date:  2019-12-31       Impact factor: 4.241

Review 10.  Pain Management in Patients with Multiple Myeloma: An Update.

Authors:  Flaminia Coluzzi; Roman Rolke; Sebastiano Mercadante
Journal:  Cancers (Basel)       Date:  2019-12-17       Impact factor: 6.639

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