| Literature DB >> 29513019 |
Lihui Zhu1,2, Long Zhang1,2,3, Sanzhong Luo1,2,3.
Abstract
A chiral primary amine catalyzed oxidative β-C-H functionalization of ketone is described. The reaction proceeds via ketone enamine oxidation by IBX and enables highly enantioselective remote C-H functionalization of both cyclic and acyclic ketones, generating chiral ketones bearing β-stereocenters.Entities:
Year: 2018 PMID： 29513019 DOI： 10.1021/acs.orglett.8b00508
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005