Andrew T Strong1,2, Gautam Sharma3, Chao Tu3,4, Ali Aminian3, James B Young5,6,7, John Rodriguez3,5, Matthew Kroh3,5,8. 1. Department of General Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk A-100, Cleveland, OH, 44195, USA. stronga@ccf.org. 2. Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA. stronga@ccf.org. 3. Department of General Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk A-100, Cleveland, OH, 44195, USA. 4. Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA. 5. Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA. 6. Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH, USA. 7. Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA. 8. Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Abstract
BACKGROUND: Weight loss following bariatric surgery can improve cardiac function among patients with heart failure (HF). However, perioperative morbidity of bariatric surgery has not been evaluated in patients with HF. STUDY DESIGN: The National Surgical Quality Improvement Project (NSQIP) database for 2006-2014 was queried to identify patients undergoing adjustable gastric band, gastric bypass, sleeve gastrectomy, and biliopancreatic diversion-duodenal switch. Patients with HF were propensity matched to a control group without HF (1:5). Univariate analyses evaluated differences in complications, and multivariate analysis was completed to predict all-cause morbidity. RESULTS: There were 237 patients identified with HF (mean age 52.8 years, 59.9% female, mean body mass index 50.6 kg/m2) matched to 1185 controls without HF who underwent bariatric surgery. Preoperatively, patients with HF were more likely to be taking antihypertensive medication and have undergone prior percutaneous cardiac intervention and cardiac surgery. There was no difference in operative time, surgical site infections, acute renal failure, re-intubation, or myocardial infarction. HF was associated with increased likelihood of length of stay more than 7 days, likelihood to remain ventilated > 48 h, venous thromboembolism, and reoperation. For patients with HF, the adjusted odds ratio for all-cause morbidity was 2.09 (1.32-3.22). CONCLUSION: The NSQIP definition of HF, which includes recent hospitalization for HF exacerbation or new HF diagnosis 30 days prior to surgery, predicts a more than two-fold increase in odds of morbidity following bariatric surgery. This must be balanced with the longer-term potential benefits of weight loss and associated improvement in cardiac function in this population.
BACKGROUND:Weight loss following bariatric surgery can improve cardiac function among patients with heart failure (HF). However, perioperative morbidity of bariatric surgery has not been evaluated in patients with HF. STUDY DESIGN: The National Surgical Quality Improvement Project (NSQIP) database for 2006-2014 was queried to identify patients undergoing adjustable gastric band, gastric bypass, sleeve gastrectomy, and biliopancreatic diversion-duodenal switch. Patients with HF were propensity matched to a control group without HF (1:5). Univariate analyses evaluated differences in complications, and multivariate analysis was completed to predict all-cause morbidity. RESULTS: There were 237 patients identified with HF (mean age 52.8 years, 59.9% female, mean body mass index 50.6 kg/m2) matched to 1185 controls without HF who underwent bariatric surgery. Preoperatively, patients with HF were more likely to be taking antihypertensive medication and have undergone prior percutaneous cardiac intervention and cardiac surgery. There was no difference in operative time, surgical site infections, acute renal failure, re-intubation, or myocardial infarction. HF was associated with increased likelihood of length of stay more than 7 days, likelihood to remain ventilated > 48 h, venous thromboembolism, and reoperation. For patients with HF, the adjusted odds ratio for all-cause morbidity was 2.09 (1.32-3.22). CONCLUSION: The NSQIP definition of HF, which includes recent hospitalization for HF exacerbation or new HF diagnosis 30 days prior to surgery, predicts a more than two-fold increase in odds of morbidity following bariatric surgery. This must be balanced with the longer-term potential benefits of weight loss and associated improvement in cardiac function in this population.
Authors: R Padwal; F A McAlister; J J V McMurray; M R Cowie; M Rich; S Pocock; K Swedberg; A Maggioni; G Gamble; C Ariti; N Earle; G Whalley; K K Poppe; R N Doughty; A Bayes-Genis Journal: Int J Obes (Lond) Date: 2013-10-31 Impact factor: 5.095
Authors: William R Miranda; John A Batsis; Michael G Sarr; Maria L Collazo-Clavell; Matthew M Clark; Virend K Somers; Francisco Lopez-Jimenez Journal: Obes Surg Date: 2013-07 Impact factor: 4.129
Authors: Sriram S Nathan; Pouya Iranmanesh; Igor D Gregoric; Mehmet H Akay; Sachin Kumar; Bindu H Akkanti; Ismael A Salas de Armas; Manish Patel; Melissa M Felinski; Shinil K Shah; Kulvinder S Bajwa; Biswajit Kar Journal: ESC Heart Fail Date: 2021-01-24