Literature DB >> 2951016

Enzymatic cleavage of various fluorinated pyrimidine nucleosides to 5-fluorouracil and their antiproliferative activities in human and murine tumor cells.

M Miwa, A Cook, H Ishitsuka.   

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Year:  1986        PMID： 2951016     DOI： 10.1248/cpb.34.4225

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


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  7 in total

1.  Inhibitory effects of fluorinated pyrimidines, 5'-DFUR, UFT and T-506, in a model of hepatic metastasis of mouse colon 26 adenocarcinoma-assessment of inhibitory activity and adverse reactions at the maximum tolerated dose.

Authors:  K Tazawa; T Sakamoto; Y Kuroki; I Yamashita; M Okamoto; S Katuyama; M Fujimaki
Journal:  Clin Exp Metastasis       Date:  1997-05       Impact factor: 5.150

2.  Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine.

Authors:  H Eda; K Fujimoto; S Watanabe; M Ura; A Hino; Y Tanaka; K Wada; H Ishitsuka
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

3.  Role of thymidine phosphorylase and orotate phosphoribosyltransferase mRNA expression and its ratio to dihydropyrimidine dehydrogenase in the prognosis and clinicopathological features of patients with pancreatic cancer.

Authors:  Kotaro Miyake; Satoru Imura; Tomoharu Yoshizumi; Tetsuya Ikemoto; Yuji Morine; Mitsuo Shimada
Journal:  Int J Clin Oncol       Date:  2007-04-27       Impact factor: 3.402

4.  5'-Deoxy-5-fluorouridine improves cachexia by a mechanism independent of its antiproliferative action in colon 26 adenocarcinoma-bearing mice.

Authors:  H Eda; Y Tanaka; H Ishitsuka
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

5.  Antitumor effects of 5'-deoxy-5-fluorouridine in combination with recombinant human interleukin 2 on murine colon carcinoma 26.

Authors:  K Midoro; K Gotoh; T Houkan; K Yukishige; K Fujiwara; K Ootsu
Journal:  Jpn J Cancer Res       Date:  1997-03

6.  Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with radiation therapy in mice bearing colon 26 adenocarcinoma.

Authors:  T Ishikawa; Y Tanaka; H Ishitsuka; T Ohkawa
Journal:  Jpn J Cancer Res       Date:  1989-06

7.  Cytokines induce uridine phosphorylase in mouse colon 26 carcinoma cells and make the cells more susceptible to 5'-deoxy-5-fluorouridine.

Authors:  H Eda; K Fujimoto; S Watanabe; T Ishikawa; T Ohiwa; K Tatsuno; Y Tanaka; H Ishitsuka
Journal:  Jpn J Cancer Res       Date:  1993-03
  7 in total

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