Literature DB >> 2951015

Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding.

J Graf, Y Iwamoto, M Sasaki, G R Martin, H K Kleinman, F A Robey, Y Yamada.   

Abstract

We have probed for active sites in the B1 chain of laminin using synthetic peptides comprising certain regions of its amino acid sequence as deduced from cDNA clones. An antibody to a 19-mer from domain III inhibited attachment of HT-1080 and CHO cells to laminin, while the peptide itself was inactive. A nearby peptide (CDPGYIGSR) from domain III with homology to epidermal growth factor was synthesized and found to be one of the principle sites in laminin mediating cell attachment, migration, and receptor binding.

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Year:  1987        PMID： 2951015     DOI： 10.1016/0092-8674(87)90707-0

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  129 in total

1.  An IKLLI-containing peptide derived from the laminin alpha1 chain mediating heparin-binding, cell adhesion, neurite outgrowth and proliferation, represents a binding site for integrin alpha3beta1 and heparan sulphate proteoglycan.

Authors:  K Tashiro; A Monji; I Yoshida; Y Hayashi; K Matsuda; N Tashiro; Y Mitsuyama
Journal:  Biochem J       Date:  1999-05-15       Impact factor: 3.857

2.  Characterization of two monoclonal antibodies directed against the 67 kDa high affinity laminin receptor and application for the study of breast carcinoma progression.

Authors:  S Martignone; R Pellegrini; E Villa; N N Tandon; A Mastroianni; E Tagliabue; S Ménard; M I Colnaghi
Journal:  Clin Exp Metastasis       Date:  1992-11       Impact factor: 5.150

Review 3.  Tissue engineering in the vascular graft.

Authors:  S P Massia; J A Hubbell
Journal:  Cytotechnology       Date:  1992       Impact factor: 2.058

4.  Snake venom platelet inhibitor (rhodostomin) inhibits cell-attachment.

Authors:  L C Au; H H Lin; G W Teh; S B Lin
Journal:  In Vitro Cell Dev Biol       Date:  1992 Sep-Oct

5.  Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans.

Authors:  V Kodoyianni; E M Maine; J Kimble
Journal:  Mol Biol Cell       Date:  1992-11       Impact factor: 4.138

Review 6.  Extracellular matrix and neuronal movement.

Authors:  P Liesi
Journal:  Experientia       Date:  1990-09-15

7.  Laminin-mediated adhesion in metastatic rat rhabdomyosarcoma cell lines involves prominent interactions with the laminin E8 fragment.

Authors:  J C Lissitzky; M Bouzon; E Loret; M F Poupon; P M Martin
Journal:  Clin Exp Metastasis       Date:  1989 Jul-Aug       Impact factor: 5.150

8.  Focal adhesion kinase is activated in invading fibrosarcoma cells and regulates metastasis.

Authors:  Masuo Hanada; Kazuhiro Tanaka; Yoshihiro Matsumoto; Fumihiko Nakatani; Riku Sakimura; Tomoya Matsunobu; Xu Li; Takamitsu Okada; Tomoyuki Nakamura; Minoru Takasaki; Yukihide Iwamoto
Journal:  Clin Exp Metastasis       Date:  2005       Impact factor: 5.150

9.  Control pathways of the 67 kDa laminin binding protein: surface expression and activity of a new ligand binding domain.

Authors:  T H Landowski; S Uthayakumar; J R Starkey
Journal:  Clin Exp Metastasis       Date:  1995-09       Impact factor: 5.150

10.  Adhesion polypeptides are useful for the prevention of peritoneal dissemination of gastric cancer.

Authors:  T Matsuoka; K Hirakawa; Y S Chung; M Yashiro; S Nishimura; T Sawada; I Saiki; M Sowa
Journal:  Clin Exp Metastasis       Date:  1998-05       Impact factor: 5.150
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