Literature DB >> 29509380

[Enzymatic biocatalysis in chemical synthesis of pharmaceuticals].

A M Bezborodov, N A Zagustina.   

Abstract

In this review we summarize the available research on enzymatic biocatalysis in the chemical synthesis of drugs. We focus on oxydoreductsases, particularly ketoreductases, that are widely used in biotechnological processes: alpha- and omega-transaminases, lipases, nitrile hydrolases, and aldolases. The potential for the extended use of novel enzymes produced via bioengineering is discussed.

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Year:  2016        PMID： 29509380

Source DB:  PubMed          Journal:  Prikl Biokhim Mikrobiol        ISSN： 0555-1099


  4 in total

1.  Potential of the Signal Peptide Derived from the PAS_chr3_0030 Gene Product for Secretory Expression of Valuable Enzymes in Pichia pastoris.

Authors:  Qi Shen; Xiao-Ting Zhou; Qian Guo; Yu-Zhen Xue; Ya-Ping Xue; Yu-Guo Zheng
Journal:  Appl Environ Microbiol       Date:  2022-04-18       Impact factor: 5.005

Review 2.  Whole Cells as Biocatalysts in Organic Transformations.

Authors:  Fabián Garzón-Posse; Liliana Becerra-Figueroa; José Hernández-Arias; Diego Gamba-Sánchez
Journal:  Molecules       Date:  2018-05-25       Impact factor: 4.411

Review 3.  High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from l-Phenylalanine via Linear and Divergent Enzymatic Cascades.

Authors:  Maria L Corrado; Tanja Knaus; Ulrich Schwaneberg; Francesco G Mutti
Journal:  Org Process Res Dev       Date:  2022-03-28       Impact factor: 3.858

4.  Immobilized Lipase in Resolution of Ketoprofen Enantiomers: Examination of Biocatalysts Properties and Process Characterization.

Authors:  Oliwia Degórska; Daria Szada; Agata Zdarta; Wojciech Smułek; Teofil Jesionowski; Jakub Zdarta
Journal:  Pharmaceutics       Date:  2022-07-11       Impact factor: 6.525
  4 in total

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