| Literature DB >> 29508865 |
Sanggil Kim1, Bong Hyun Sung2, Sun Chang Kim3, Hyun Soo Lee1.
Abstract
l-Dihydroxyphenylalanine (DOPA) was biosynthesized by a tyrosine-phenol lyase from catechol, pyruvate, and ammonia in Escherichia coli, and the biosynthesized amino acid was directly incorporated into proteins. Three biochemical experiments with mutant proteins containing DOPA confirmed the genetic incorporation of biosynthesized DOPA, and revealed its potential for various biochemical applications.Entities:
Year: 2018 PMID: 29508865 DOI: 10.1039/c8cc00281a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222