Literature DB >> 29507030

Delayed diagnosis of chronic postoperative sternal infection: a rare case of sternal tuberculosis.

Victoria Rizzo1, Yousuf Salmasi1, Michael Hunter2, Pushpinder Sidhu1.   

Abstract

Sternal osteomyelitis secondary to mycobacterium tuberculosis (TB) is rare, with <1% of musculoskeletal TB cases reported. The recurrent scenario is unresolving infection and delayed diagnosis. A 75-year-old woman presented with a persistently discharging sternal wound 10 months after coronary artery bypass grafting. Multiple antibiotics, wound debridement and removal of sternal wires was attempted; however, progression to local osteomyelitis and sternoclavicular joint destruction occurred. Tissue biopsies were finally sent for mycobacterial culture testing positive for Mycobacterium tuberculosis High index of suspicion is necessary for diagnosis of sternal tuberculosis, confirmed through timely microbiological investigations. MRI may identify soft-tissue and bone oedema characteristic of TB osteomyelitis. This patient had no TB risk factors. The source of infection is unclear and warrants further investigation. Sternal TB osteomyelitis is uncommon and largely reported through case reports, thus management and indications for surgery remain undefined. If sensitive, standard TB four-drug regimen may be trialled. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  bone and joint infections; cardiothoracic surgery; infections; infectious diseases

Mesh:

Substances:

Year:  2018        PMID: 29507030      PMCID: PMC5847847          DOI: 10.1136/bcr-2017-223650

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

Review 1.  Sternal tuberculosis after sternotomy for coronary artery bypass surgery: a case report and review of the literature.

Authors:  Kirun Gopal; Austin Raj; M R Rajesh; S K Prabhu; Jayasree Geothe
Journal:  J Thorac Cardiovasc Surg       Date:  2007-05       Impact factor: 5.209

Review 2.  Mycobacterium chimaera and cardiac surgery.

Authors:  Andrew J Stewardson; Rhonda L Stuart; Allen C Cheng; Paul Dr Johnson
Journal:  Med J Aust       Date:  2017-02-20       Impact factor: 7.738

3.  Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue.

Authors:  Timo Ulrichs; Michael Lefmann; Maja Reich; Lars Morawietz; Andreas Roth; Volker Brinkmann; George A Kosmiadi; Peter Seiler; Peter Aichele; Helmut Hahn; Veit Krenn; Ulf B Göbel; Stefan H E Kaufmann
Journal:  J Pathol       Date:  2005-04       Impact factor: 7.996

4.  Sternal tuberculosis.

Authors:  R Sachdeva; S Sachdeva; S Arora
Journal:  Ann Med Health Sci Res       Date:  2013-11

5.  Tuberculosis of the sternum: a clinical study.

Authors:  S A Khan; M K Varshney; A S Hasan; A Kumar; V Trikha
Journal:  J Bone Joint Surg Br       Date:  2007-06

6.  Risk factors for sternal wound infection and mid-term survival following coronary artery bypass surgery.

Authors:  John C Y Lu; Antony D Grayson; Pankaj Jha; Arun K Srinivasan; Brian M Fabri
Journal:  Eur J Cardiothorac Surg       Date:  2003-06       Impact factor: 4.191

Review 7.  Sternal mycobacterial infections.

Authors:  Shi-Min Yuan
Journal:  Ann Thorac Med       Date:  2016 Apr-Jun       Impact factor: 2.219

  7 in total
  4 in total

1.  Isolated primary cold abscess of the sternum: a case report.

Authors:  Lovenish Bains; Pawan Lal; Tirlok Chand; Kamal Kishore Gautam; Mohd Yasir Beg; Pritesh Kumar
Journal:  J Med Case Rep       Date:  2019-08-25

Review 2.  Diagnosis and management of sternoclavicular joint infections: a literature review.

Authors:  Sadia Tasnim; Ali Shirafkan; Ikenna Okereke
Journal:  J Thorac Dis       Date:  2020-08       Impact factor: 2.895

3.  Mycobacterium tuberculosis Surgical Site Infection after Cardiac Surgery in the COVID-19 Era: A Case Report.

Authors:  Giulia Parolari; Chiara Sepulcri; Antonio Salsano; Daniele Roberto Giacobbe; Anna Marchese; Ramona Barbieri; Antonio Guadagno; Bruno Spina; Francesco Santini; Matteo Bassetti
Journal:  Infect Dis Rep       Date:  2022-02-07

4.  Sternal Tuberculosis: Case Series of Two Cases.

Authors:  Adnan Asif; Lokesh Dabral
Journal:  J Orthop Case Rep       Date:  2021-11
  4 in total

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