Valirie N Agbor1, Mickael Essouma2, Ntobeko A B Ntusi3, Ulrich Flore Nyaga2, Jean Joel Bigna4, Jean Jacques Noubiap5. 1. Ibal Sub-divisional Hospital, Oku, North-west Region, Cameroon. 2. Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon. 3. Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa; Cape Universities Body Imaging Center, University of Cape Town, Cape Town, South Africa; Hatter Institute for Cardiovascular Research in Africa, Department of Medicine, University of Cape Town, Cape Town, South Africa. 4. Faculty of Medicine, University of Paris Sud XI, Le Kremlin-Bicêtre, France. 5. Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa. Electronic address: noubiapjj@yahoo.fr.
Abstract
OBJECTIVE: To summarise available data on the prevalence, aetiology, treatment and prognosis of heart failure (HF) in sub-Saharan Africa (SSA). SETTING: This systematic review and meta-analysis included data from individuals recruited in primary to tertiary health facilities in SSA. PARTICIPANTS: All published and unpublished literatures between January 1, 1996 and June 23, 2017, of individuals aged 12years and older and residing in sub-Saharan Africa. They must be of African descent. OUTCOME: Number of heart failure admissions into general wards or HF clinics; number of cases of the different aetiologies of HF; number of participants on the different medications for HF; number of cases of all-cause mortality in participants with HF, and the predictors of all-cause mortality. Due to a limited word count, only results on the aetiologies of HF will be presented in the abstract. RESULTS: Thirty five full text articles were selected after screening of an initial 3785 titles and abstract. Hypertensive heart disease (HHD) (39.2% [95% CI=32.6-45.9]) was the commonest cause of HF in SSA, followed by cardiomyopathies (CMO) (21.4% [95% CI=16.0-27.2]) and rheumatic heart disease (RHD) (14.1% [95% CI=10.0-18.8]). Ischaemic heart disease (7.2% [95% CI=4.1-11.0]) was rare. CONCLUSION: HHD, CMO and RHD are the most common causes of HF in SSA, with HHD and CMO responsible for over 50% of the cases. Also, the last two decades have witnessed a relative reduction in the prevalence of RHD below 15.0%.
OBJECTIVE: To summarise available data on the prevalence, aetiology, treatment and prognosis of heart failure (HF) in sub-Saharan Africa (SSA). SETTING: This systematic review and meta-analysis included data from individuals recruited in primary to tertiary health facilities in SSA. PARTICIPANTS: All published and unpublished literatures between January 1, 1996 and June 23, 2017, of individuals aged 12years and older and residing in sub-Saharan Africa. They must be of African descent. OUTCOME: Number of heart failure admissions into general wards or HF clinics; number of cases of the different aetiologies of HF; number of participants on the different medications for HF; number of cases of all-cause mortality in participants with HF, and the predictors of all-cause mortality. Due to a limited word count, only results on the aetiologies of HF will be presented in the abstract. RESULTS: Thirty five full text articles were selected after screening of an initial 3785 titles and abstract. Hypertensive heart disease (HHD) (39.2% [95% CI=32.6-45.9]) was the commonest cause of HF in SSA, followed by cardiomyopathies (CMO) (21.4% [95% CI=16.0-27.2]) and rheumatic heart disease (RHD) (14.1% [95% CI=10.0-18.8]). Ischaemic heart disease (7.2% [95% CI=4.1-11.0]) was rare. CONCLUSION:HHD, CMO and RHD are the most common causes of HF in SSA, with HHD and CMO responsible for over 50% of the cases. Also, the last two decades have witnessed a relative reduction in the prevalence of RHD below 15.0%.
Authors: Gasnat Shaboodien; Timothy F Spracklen; Stephen Kamuli; Polycarp Ndibangwi; Carla Van Niekerk; Ntobeko A B Ntusi Journal: Cardiovasc Diagn Ther Date: 2020-04
Authors: Alice Kidder Bukhman; Vizir Jean Paul Nsengimana; Mindy C Lipsitz; Patricia C Henwood; Endale Tefera; Shada A Rouhani; Damas Dukundane; Gene Y Bukhman Journal: Curr Cardiol Rep Date: 2019-08-31 Impact factor: 2.931
Authors: Walter Espeche; Martin R Salazar; Rodrigo Sabio; Alejandro Diaz; Carlos Leiva Sisnieguez; Daniel Olano; Eduardo Balbin; Nicolas Renna; Pedro Grosse; Roberto A Flores; Ana C Lagos; Pablo Ferrer; Silvia Poppe; Facundo Risso Patron; Victor D Sotnieczuk Stasiuk; Elina Valentini; Jose R Cardozo; Jose R Romano; Roberto Parodi; Horacio Carbajal Journal: J Clin Hypertens (Greenwich) Date: 2020-02-17 Impact factor: 3.738