H T Chu1, I Godin2, N T Phuong1, L H Nguyen1, T T M Hiep3, O Michel4. 1. Pham Ngoc Thach Hospital, Ho Chi Minh City, Viet Nam. 2. School of Public Health, Université Libre de Bruxelles (ULB), Brussels, Belgium. 3. Department of Paediatrics, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam. 4. Clinic of Immuno-Allergology, Centre Hospitalier Universitaire Brugmann, ULB, Brussels, Belgium.
Abstract
OBJECTIVE: To evaluate the prevalence of and risk factors for allergen sensitisation among patients with chronic respiratory disease (CRD) in southern Viet Nam. DESIGN: An environmental questionnaire and skin prick tests for airborne and food allergens were administered to patients with CRD, defined as individuals with respiratory symptoms and lung function defects. RESULTS: Of 610 CRD patients, 56% had chronic obstructive pulmonary disease and 31% were asthma patients; 80% were males. The most frequent sensitisers were dust mites (Dermatophagoides farinae 22%, Blomia tropicalis 19%, D. pteronyssinus 18%) and cockroach droppings (13%). Among study participants, 37% were from rural settings and 36% from urban areas, whereas 27% had migrated from rural to urban areas. Compared with people from rural areas, being born in an urban area was a risk factor for sensitisation to mites (OR 1.56, 95%CI 1.11-2.20, P < 0.02). In multivariate analysis, place of birth remained a risk factor for mite sensitisation. Compared with the native urban population, the risk of mite sensitisation was not significantly different among patients born in rural areas and those migrating to urban areas. CONCLUSION: Dust mites and cockroach droppings were the most frequent allergens among people with CRD in the south of Viet Nam. Compared with the urban population, being native to a rural area was protective against mite sensitisation, but this effect ceased to be significant after migration from rural to urban areas.
OBJECTIVE: To evaluate the prevalence of and risk factors for allergen sensitisation among patients with chronic respiratory disease (CRD) in southern Viet Nam. DESIGN: An environmental questionnaire and skin prick tests for airborne and food allergens were administered to patients with CRD, defined as individuals with respiratory symptoms and lung function defects. RESULTS: Of 610 CRDpatients, 56% had chronic obstructive pulmonary disease and 31% were asthmapatients; 80% were males. The most frequent sensitisers were dust mites (Dermatophagoides farinae 22%, Blomia tropicalis 19%, D. pteronyssinus 18%) and cockroach droppings (13%). Among study participants, 37% were from rural settings and 36% from urban areas, whereas 27% had migrated from rural to urban areas. Compared with people from rural areas, being born in an urban area was a risk factor for sensitisation to mites (OR 1.56, 95%CI 1.11-2.20, P < 0.02). In multivariate analysis, place of birth remained a risk factor for mite sensitisation. Compared with the native urban population, the risk of mite sensitisation was not significantly different among patients born in rural areas and those migrating to urban areas. CONCLUSION: Dust mites and cockroach droppings were the most frequent allergens among people with CRD in the south of Viet Nam. Compared with the urban population, being native to a rural area was protective against mite sensitisation, but this effect ceased to be significant after migration from rural to urban areas.
Authors: Ha Thi Chu; Isabelle Godin; Nguyễn Thanh Phương; Lan Huu Nguyen; Tran Thi Mong Hiep; Ngo Minh Xuan; Francis Corazza; Olivier Michel Journal: Asia Pac Allergy Date: 2018-10-23
Authors: Ha Thi Chu; Thanh Ngoc Tran; Virginie Doyen; Olivier Denis; Thi Thu Thuy Tran; Thi Kieu Diem Nguyen; Huu Lan Nguyen; Minh Xuan Ngo; Thi Mong Hiep Tran; Francis Corazza; Catherine Bouland; Jean-Marie Hauglustaine; Isabelle Godin; Olivier Michel Journal: World Allergy Organ J Date: 2019-11-26 Impact factor: 4.084