| Literature DB >> 29505975 |
Richard R Meehan1, John P Thomson2, Antonio Lentini3, Colm E Nestor4, Sari Pennings5.
Abstract
Recent progress in interpreting comprehensive genetic and epigenetic profiles for human cellular states has contributed new insights into the developmental origins of disease, elucidated novel signalling pathways and enhanced drug discovery programs. A similar comprehensive approach to decoding the epigenetic readouts from chemical challenges in vivo would yield new paradigms for monitoring and assessing environmental exposure in model systems and humans.Entities:
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Year: 2018 PMID: 29505975 DOI: 10.1016/j.cbpa.2018.02.006
Source DB: PubMed Journal: Curr Opin Chem Biol ISSN: 1367-5931 Impact factor: 8.822