| Literature DB >> 29504644 |
Jiantao Zhang1, Zhehui Liao1, Lianfen Chen1, Huanfeng Jiang1, Shifa Zhu1.
Abstract
A catalytic [1,3] O-to-C rearrangement from enyne-ethers was developed for the rapid synthesis of diverse bridged bicyclic systems. In this reaction, a vinyl oxonium intermediate, generated in situ from enyne-ether, was the precursor for the [1,3] O-to-C rearrangement. This versatile protocol represents the first example of catalytic [1,3] O-to-C rearrangement based on ring-expansion strategy, enabling efficient access to bridged bicyclic scaffolds.Entities:
Keywords: [1,3]-rearrangement; [3,3]-rearrangement; bridged bicycles; gold; ring-expansion reactions
Year: 2018 PMID： 29504644 DOI： 10.1002/chem.201801062
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236