Literature DB >> 29501921

A clinician friendly data warehouse oriented toward narrative reports: Dr. Warehouse.

Nicolas Garcelon1, Antoine Neuraz2, Rémi Salomon3, Hassan Faour4, Vincent Benoit4, Arthur Delapalme4, Arnold Munnich5, Anita Burgun2, Bastien Rance6.   

Abstract

INTRODUCTION: Clinical data warehouses are often oriented toward integration and exploration of coded data. However narrative reports are of crucial importance for translational research. This paper describes Dr. Warehouse®, an open source data warehouse oriented toward clinical narrative reports and designed to support clinicians' day-to-day use.
METHOD: Dr. Warehouse relies on an original database model to focus on documents in addition to facts. Besides classical querying functionalities, the system provides an advanced search engine and Graphical User Interfaces adapted to the exploration of text. Dr. Warehouse is dedicated to translational research with cohort recruitment capabilities, high throughput phenotyping and patient centric views (including similarity metrics among patients). These features leverage Natural Language Processing based on the extraction of UMLS® concepts, as well as negation and family history detection.
RESULTS: A survey conducted after 6 months of use at the Necker Children's Hospital shows a high rate of satisfaction among the users (96.6%). During this period, 122 users performed 2837 queries, accessed 4,267 patients' records and included 36,632 patients in 131 cohorts. The source code is available at this github link https://github.com/imagine-bdd/DRWH. A demonstration based on PubMed abstracts is available at https://imagine-plateforme-bdd.fr/dwh_pubmed/.
Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Computational biology; Data warehouse; Electronic health records; Information storage and retrieval; Method; Rare diseases; Software; Text-mining

Mesh:

Year:  2018        PMID: 29501921     DOI: 10.1016/j.jbi.2018.02.019

Source DB:  PubMed          Journal:  J Biomed Inform        ISSN: 1532-0464            Impact factor:   6.317


  19 in total

1.  Arterial Spin-Labeling Perfusion Imaging in the Early Stage of Sturge-Weber Syndrome.

Authors:  G Pouliquen; L Fillon; V Dangouloff-Ros; M Kuchenbuch; C Bar; N Chemaly; R Levy; C-J Roux; A Saitovitch; J Boisgontier; R Nabbout; N Boddaert
Journal:  AJNR Am J Neuroradiol       Date:  2022-09-22       Impact factor: 4.966

2.  Response to First Course of Intensified Immunosuppression in Genetically Stratified Steroid Resistant Nephrotic Syndrome.

Authors:  Anna E Mason; Ethan S Sen; Agnieszka Bierzynska; Elizabeth Colby; Maryam Afzal; Guillaume Dorval; Ania B Koziell; Maggie Williams; Olivia Boyer; Gavin I Welsh; Moin A Saleem
Journal:  Clin J Am Soc Nephrol       Date:  2020-04-21       Impact factor: 8.237

3.  ACE: the Advanced Cohort Engine for searching longitudinal patient records.

Authors:  Alison Callahan; Vladimir Polony; José D Posada; Juan M Banda; Saurabh Gombar; Nigam H Shah
Journal:  J Am Med Inform Assoc       Date:  2021-07-14       Impact factor: 4.497

4.  Diagnosis of genetic diseases in seriously ill children by rapid whole-genome sequencing and automated phenotyping and interpretation.

Authors:  Michelle M Clark; Amber Hildreth; Sergey Batalov; Yan Ding; Shimul Chowdhury; Kelly Watkins; Katarzyna Ellsworth; Brandon Camp; Cyrielle I Kint; Calum Yacoubian; Lauge Farnaes; Matthew N Bainbridge; Curtis Beebe; Joshua J A Braun; Margaret Bray; Jeanne Carroll; Julie A Cakici; Sara A Caylor; Christina Clarke; Mitchell P Creed; Jennifer Friedman; Alison Frith; Richard Gain; Mary Gaughran; Shauna George; Sheldon Gilmer; Joseph Gleeson; Jeremy Gore; Haiying Grunenwald; Raymond L Hovey; Marie L Janes; Kejia Lin; Paul D McDonagh; Kyle McBride; Patrick Mulrooney; Shareef Nahas; Daeheon Oh; Albert Oriol; Laura Puckett; Zia Rady; Martin G Reese; Julie Ryu; Lisa Salz; Erica Sanford; Lawrence Stewart; Nathaly Sweeney; Mari Tokita; Luca Van Der Kraan; Sarah White; Kristen Wigby; Brett Williams; Terence Wong; Meredith S Wright; Catherine Yamada; Peter Schols; John Reynders; Kevin Hall; David Dimmock; Narayanan Veeraraghavan; Thomas Defay; Stephen F Kingsmore
Journal:  Sci Transl Med       Date:  2019-04-24       Impact factor: 19.319

5.  The Korea Cancer Big Data Platform (K-CBP) for Cancer Research.

Authors:  Hyo Soung Cha; Jip Min Jung; Seob Yoon Shin; Young Mi Jang; Phillip Park; Jae Wook Lee; Seung Hyun Chung; Kui Son Choi
Journal:  Int J Environ Res Public Health       Date:  2019-06-28       Impact factor: 3.390

6.  Building a Semantic Health Data Warehouse in the Context of Clinical Trials: Development and Usability Study.

Authors:  Romain Lelong; Lina F Soualmia; Julien Grosjean; Mehdi Taalba; Stéfan J Darmoni
Journal:  JMIR Med Inform       Date:  2019-12-20

7.  Improving early diagnosis of rare diseases using Natural Language Processing in unstructured medical records: an illustration from Dravet syndrome.

Authors:  Tommaso Lo Barco; Mathieu Kuchenbuch; Nicolas Garcelon; Antoine Neuraz; Rima Nabbout
Journal:  Orphanet J Rare Dis       Date:  2021-07-13       Impact factor: 4.123

8.  Hepatobiliary Complications in Children with Sickle Cell Disease: A Retrospective Review of Medical Records from 616 Patients.

Authors:  Slimane Allali; Mariane de Montalembert; Valentine Brousse; Claire Heilbronner; Melissa Taylor; Josephine Brice; Elisabetta Manzali; Nicolas Garcelon; Florence Lacaille
Journal:  J Clin Med       Date:  2019-09-18       Impact factor: 4.241

Review 9.  Artificial Intelligence (AI) in Rare Diseases: Is the Future Brighter?

Authors:  Sandra Brasil; Carlota Pascoal; Rita Francisco; Vanessa Dos Reis Ferreira; Paula A Videira; And Gonçalo Valadão
Journal:  Genes (Basel)       Date:  2019-11-27       Impact factor: 4.096

10.  Healthcare trajectory of children with rare bone disease attending pediatric emergency departments.

Authors:  David Dawei Yang; Geneviève Baujat; Antoine Neuraz; Nicolas Garcelon; Claude Messiaen; Arnaud Sandrin; Gérard Cheron; Anita Burgun; Zagorka Pejin; Valérie Cormier-Daire; François Angoulvant
Journal:  Orphanet J Rare Dis       Date:  2020-01-03       Impact factor: 4.123

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