| Literature DB >> 29501086 |
Yoonhyuk Jang1, Soon-Tae Lee1, Jung-Ah Lim2, Tae-Joon Kim1, Jin-Sun Jun1, Jangsup Moon1, Jun-Sang Sunwoo3, Keun-Hwa Jung1, Kyung-Il Park4, Ki-Young Jung1, Manho Kim1, Sang Kun Lee5, Kon Chu6.
Abstract
The aim of this study was to analyze the detailed characteristics of the psychiatric symptoms in patients with anti-LGI1 encephalitis. Of 16 patients, ten showed psychiatric symptoms as the initial manifestations. All 10 patients experienced mood-related symptoms. The time to immune therapy was longer in those with initial psychiatric symptoms compared to those without them. Initial manifestation of psychiatric symptoms in patients with anti-LGI1 encephalitis may be a poor prognostic factor, at least in the short term, in that it misleads both the patients and the clinicians to neglect the typically accompanied symptoms of the disease such as faciobrachial dystonic seizure, delaying the timing of immune therapy.Entities:
Keywords: Anti-LGI1 encephalitis; Dementia; Epilepsy-related psychosis; Prognostic factor; Psychiatric symptom; Senile depression
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Year: 2018 PMID： 29501086 DOI： 10.1016/j.jneuroim.2018.02.005
Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478