Literature DB >> 29500329

Driver Oncogenes but Not as We Know Them: Targetable Fusion Genes in Breast Cancer.

Rachael Natrajan1, Andrew N J Tutt1,2, Christopher J Lord1,3.   

Abstract

<b/> Two reports in this issue of Cancer Discovery outline how the genomic composition of tumors, including the presence of intragenic gene fusions, could inform the selection of treatment approaches in aggressive forms of the disease. Cancer Discov; 8(3); 272-5. ©2018 AACRSee related article by Matissek et al., p. 336See related article by Liu et al., p. 354. ©2018 American Association for Cancer Research.

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Year:  2018        PMID： 29500329      PMCID： PMC6372062          DOI： 10.1158/2159-8290.CD-18-0091

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  10 in total

1.  Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer.

Authors:  Hui Liu; Charles J Murphy; Florian A Karreth; Kristina B Emdal; Forest M White; Olivier Elemento; Alex Toker; Gerburg M Wulf; Lewis C Cantley
Journal:  Cancer Discov       Date:  2017-12-04       Impact factor: 39.397

2.  Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma.

Authors:  Cristina Tognon; Stevan R Knezevich; David Huntsman; Calvin D Roskelley; Natalya Melnyk; Joan A Mathers; Laurence Becker; Fatima Carneiro; Nicol MacPherson; Doug Horsman; Christopher Poremba; Poul H B Sorensen
Journal:  Cancer Cell       Date:  2002-11       Impact factor: 31.743

3.  Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck.

Authors:  Marta Persson; Ywonne Andrén; Joachim Mark; Hugo M Horlings; Fredrik Persson; Göran Stenman
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-19       Impact factor: 11.205

4.  Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer.

Authors:  Karina J Matissek; Maristela L Onozato; Sheng Sun; Zongli Zheng; Andrew Schultz; Jesse Lee; Kristofer Patel; Piiha-Lotta Jerevall; Srinivas Vinod Saladi; Allison Macleay; Mehrad Tavallai; Tanja Badovinac-Crnjevic; Carlos Barrios; Nuran Beşe; Arlene Chan; Yanin Chavarri-Guerra; Marcio Debiasi; Elif Demirdögen; Ünal Egeli; Sahsuvar Gökgöz; Henry Gomez; Pedro Liedke; Ismet Tasdelen; Sahsine Tolunay; Gustavo Werutsky; Jessica St Louis; Nora Horick; Dianne M Finkelstein; Long Phi Le; Aditya Bardia; Paul E Goss; Dennis C Sgroi; A John Iafrate; Leif W Ellisen
Journal:  Cancer Discov       Date:  2017-12-14       Impact factor: 39.397

5.  Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

Authors:  Xiaoling Liu; Henne Holstege; Hanneke van der Gulden; Marcelle Treur-Mulder; John Zevenhoven; Arno Velds; Ron M Kerkhoven; Martin H van Vliet; Lodewyk F A Wessels; Johannes L Peterse; Anton Berns; Jos Jonkers
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-11       Impact factor: 11.205

6.  Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system.

Authors:  R Torres; M C Martin; A Garcia; Juan C Cigudosa; J C Ramirez; S Rodriguez-Perales
Journal:  Nat Commun       Date:  2014-06-03       Impact factor: 14.919

7.  Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.

Authors:  Dan R Robinson; Shanker Kalyana-Sundaram; Yi-Mi Wu; Sunita Shankar; Xuhong Cao; Bushra Ateeq; Irfan A Asangani; Matthew Iyer; Christopher A Maher; Catherine S Grasso; Robert J Lonigro; Michael Quist; Javed Siddiqui; Rohit Mehra; Xiaojun Jing; Thomas J Giordano; Michael S Sabel; Celina G Kleer; Nallasivam Palanisamy; Rachael Natrajan; Maryou B Lambros; Jorge S Reis-Filho; Chandan Kumar-Sinha; Arul M Chinnaiyan
Journal:  Nat Med       Date:  2011-11-20       Impact factor: 53.440

8.  The landscape and therapeutic relevance of cancer-associated transcript fusions.

Authors:  K Yoshihara; Q Wang; W Torres-Garcia; S Zheng; R Vegesna; H Kim; R G W Verhaak
Journal:  Oncogene       Date:  2014-12-15       Impact factor: 9.867

9.  The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.

Authors:  Jeffrey S Ross; Kai Wang; Juliann Chmielecki; Laurie Gay; Adrienne Johnson; Jacob Chudnovsky; Roman Yelensky; Doron Lipson; Siraj M Ali; Julia A Elvin; Jo-Anne Vergilio; Steven Roels; Vincent A Miller; Brooke N Nakamura; Adam Gray; Michael K Wong; Philip J Stephens
Journal:  Int J Cancer       Date:  2015-09-08       Impact factor: 7.396

10.  Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers.

Authors:  Jamunarani Veeraraghavan; Ying Tan; Xi-Xi Cao; Jin Ah Kim; Xian Wang; Gary C Chamness; Sourindra N Maiti; Laurence J N Cooper; Dean P Edwards; Alejandro Contreras; Susan G Hilsenbeck; Eric C Chang; Rachel Schiff; Xiao-Song Wang
Journal:  Nat Commun       Date:  2014-08-07       Impact factor: 14.919
  10 in total
  2 in total

1.  Prognostic Outcomes of Signet Ring Cell Carcinoma of the Breast.

Authors:  Maahum Mehdi; Amanda L Kong; Julia Frebault; Shane Huang; Chiang-Ching Huang; Chandler S Cortina
Journal:  J Surg Res       Date:  2021-04-03       Impact factor: 2.417

2.  Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening.

Authors:  Gabriele Picco; Elisabeth D Chen; Luz Garcia Alonso; Fiona M Behan; Emanuel Gonçalves; Graham Bignell; Angela Matchan; Beiyuan Fu; Ruby Banerjee; Elizabeth Anderson; Adam Butler; Cyril H Benes; Ultan McDermott; David Dow; Francesco Iorio; Euan Stronach; Fengtang Yang; Kosuke Yusa; Julio Saez-Rodriguez; Mathew J Garnett
Journal:  Nat Commun       Date:  2019-05-16       Impact factor: 14.919
  2 in total

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