Epilepsy and handicap from birth to age 36.

Fifty-five subjects with epilepsy were identified in the first 36 years of the 1946 birth cohort study. In 37 cases there was neither evident cause for the epilepsy nor associated brain-damage and these are referred to as 'uncomplicated', the rest as 'complicated'. Subjects with epilepsy came from poorer social backgrounds than the rest of the cohort. Mortality for both the complicated and uncomplicated groups was high. The educational and occupational achievements, marriage and parenthood, self-esteem and psychiatric morbidity of those surviving to adult life were compared with individually matched controls drawn from the same population. For the uncomplicated group there was no evidence of handicap at age 26, but 10 years later handicap was evident in this group in the economic sphere and in self-esteem.