Literature DB >> 29499378

The integrated stress response system in cardiovascular disease.

Diana Santos-Ribeiro1, Laurent Godinas2, Charles Pilette3, Frédéric Perros4.   

Abstract

The integrated stress response system represents an ancillary, extremely conserved signalling pathway present in virtually all eukaryotic cells, which plays an important part in the pathophysiology of several disorders such as cancer and neurodegeneration. However, its role in the cardiovascular system remains largely elusive. Hence, this review aims to acknowledge recent findings regarding the action of the eIF2α kinases in the cardiovascular system and their role in the pathophysiology of related disorders.
Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 29499378     DOI： 10.1016/j.drudis.2018.02.008

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  4 in total

1.  Integrated Stress Response Couples Mitochondrial Protein Translation With Oxidative Stress Control.

Authors:  Guangyu Zhang; Xiaoding Wang; Chao Li; Qinfeng Li; Yu A An; Xiang Luo; Yingfeng Deng; Thomas G Gillette; Philipp E Scherer; Zhao V Wang
Journal:  Circulation       Date:  2021-09-29       Impact factor: 29.690

Review 2.  Cellular Stress in the Pathogenesis of Muscular Disorders-From Cause to Consequence.

Authors:  Alexander Mensch; Stephan Zierz
Journal:  Int J Mol Sci       Date:  2020-08-13       Impact factor: 5.923

Review 3.  Hypoxia and the integrated stress response promote pulmonary hypertension and preeclampsia: Implications in drug development.

Authors:  Xiang-Qun Hu; Lubo Zhang
Journal:  Drug Discov Today       Date:  2021-07-22       Impact factor: 7.851

4.  XPRESSyourself: Enhancing, standardizing, and automating ribosome profiling computational analyses yields improved insight into data.

Authors:  Jordan A Berg; Jonathan R Belyeu; Jeffrey T Morgan; Yeyun Ouyang; Alex J Bott; Aaron R Quinlan; Jason Gertz; Jared Rutter
Journal:  PLoS Comput Biol       Date:  2020-01-31       Impact factor: 4.475
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.