Literature DB >> 29499148

Engineering Human Bone Marrow Proxies.

Paul E Bourgine1, Ivan Martin2, Timm Schroeder3.   

Abstract

Recent advances in engineering complex organs in vitro inspire the development of human bone marrow equivalents to foster scientific discovery and innovative therapeutics. Here, we discuss challenges in generating relevant human bone marrow proxies, potential design principles, and future directions.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 29499148     DOI： 10.1016/j.stem.2018.01.002

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  8 in total

1.  In vitro biomimetic engineering of a human hematopoietic niche with functional properties.

Authors:  Paul E Bourgine; Thibaut Klein; Anna M Paczulla; Takafumi Shimizu; Leo Kunz; Konstantinos D Kokkaliaris; Daniel L Coutu; Claudia Lengerke; Radek Skoda; Timm Schroeder; Ivan Martin
Journal:  Proc Natl Acad Sci U S A       Date:  2018-06-04       Impact factor: 11.205

2.  Skeletal Stem Cells as the Developmental Origin of Cellular Niches for Hematopoietic Stem and Progenitor Cells.

Authors:  Thomas H Ambrosi; Charles K F Chan
Journal:  Curr Top Microbiol Immunol       Date:  2021       Impact factor: 4.291

Review 3.  Engineering human hematopoietic environments through ossicle and bioreactor technologies exploitation.

Authors:  Pia Sommerkamp; François E Mercier; Adam C Wilkinson; Dominique Bonnet; Paul E Bourgine
Journal:  Exp Hematol       Date:  2020-12-02       Impact factor: 3.084

4.  Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches.

Authors:  Andrés García-García; Thibaut Klein; Gordian Born; Morgane Hilpert; Arnaud Scherberich; Claudia Lengerke; Radek C Skoda; Paul E Bourgine; Ivan Martin
Journal:  Proc Natl Acad Sci U S A       Date:  2021-10-05       Impact factor: 11.205

5.  Fate Distribution and Regulatory Role of Human Mesenchymal Stromal Cells in Engineered Hematopoietic Bone Organs.

Authors:  Paul E Bourgine; Kristin Fritsch; Sebastien Pigeot; Hitoshi Takizawa; Leo Kunz; Konstantinos D Kokkaliaris; Daniel L Coutu; Markus G Manz; Ivan Martin; Timm Schroeder
Journal:  iScience       Date:  2019-08-07

6.  Apoptosis repressor with caspase recruitment domain (ARC) promotes bone regeneration of bone marrow-derived mesenchymal stem cells by activating Fgf-2/PI3K/Akt signaling.

Authors:  Longwei Hu; Yang Wang; Hongya Pan; Kathreena Kadir; Jin Wen; Siyi Li; Chenping Zhang
Journal:  Stem Cell Res Ther       Date:  2021-03-16       Impact factor: 6.832

Review 7.  In Vitro Modeling of Non-Solid Tumors: How Far Can Tissue Engineering Go?

Authors:  Sandra Clara-Trujillo; Gloria Gallego Ferrer; José Luis Gómez Ribelles
Journal:  Int J Mol Sci       Date:  2020-08-11       Impact factor: 5.923

Review 8.  The physical microenvironment of hematopoietic stem cells and its emerging roles in engineering applications.

Authors:  Pan Zhang; Chen Zhang; Jing Li; Jiyang Han; Xiru Liu; Hui Yang
Journal:  Stem Cell Res Ther       Date:  2019-11-19       Impact factor: 6.832
  8 in total

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