Literature DB >> 29496815

Microinjecting Lentivirus into Mouse Embryos.

Shirley Pease.   

Abstract

This protocol describes the injection of lentivirus into the perivitelline space of fertilized oocytes. Embryos usually survive lentiviral injection well because only the zona is pierced.
© 2018 Cold Spring Harbor Laboratory Press.

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Year:  2018        PMID: 29496815     DOI: 10.1101/pdb.prot093914

Source DB:  PubMed          Journal:  Cold Spring Harb Protoc        ISSN: 1559-6095


  1 in total

1.  Single AAV-mediated CRISPR-Nme2Cas9 efficiently reduces mutant hTTR expression in a transgenic mouse model of transthyretin amyloidosis.

Authors:  Jinkun Wen; Tianqi Cao; Jinni Wu; Yuxi Chen; Shengyao Zhi; Yanming Huang; Peilin Zhen; Guanglan Wu; Lars Aagaard; Jianxin Zhong; Puping Liang; Junjiu Huang
Journal:  Mol Ther       Date:  2021-05-14       Impact factor: 11.454

  1 in total

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