M Drake-Pérez1,2, B M A Delattre3, J Boto1, A Fitsiori1, K-O Lovblad1, S Boudabbous3, M I Vargas4. 1. From the Division of Diagnostic and Interventional Neuroradiology (M.D.-P., J.B., A.F., K.-O.L., M.I.V.), Geneva University Hospitals and Faculty of Medicine of Geneva, Geneva, Switzerland. 2. Department of Radiology (M.D.-P.), University Hospital Marqués de Valdecilla-Instituto de Investigación Sanitaria Valdecilla, Santander, Spain. 3. Division of Radiology (B.M.A.D., S.B.), Geneva University Hospitals, Geneva, Switzerland. 4. From the Division of Diagnostic and Interventional Neuroradiology (M.D.-P., J.B., A.F., K.-O.L., M.I.V.), Geneva University Hospitals and Faculty of Medicine of Geneva, Geneva, Switzerland maria.i.vargas@hcuge.ch.
Abstract
BACKGROUND AND PURPOSE: SyMRI is a technique developed to perform quantitative MR imaging. Our aim was to analyze its potential use for measuring relaxation times of normal components of the spine and to compare them with values found in the literature using relaxometry and other techniques. MATERIALS AND METHODS: Thirty-two spine MR imaging studies (10 cervical, 5 dorsal, 17 lumbosacral) were included. A modified multiple-dynamic multiple-echo sequence was added and processed to obtain quantitative T1 (millisecond), T2 (millisecond), and proton density (percentage units [pu]) maps for each patient. An ROI was placed on representative areas for CSF, spinal cord, intervertebral discs, and vertebral bodies, to measure their relaxation. RESULTS: Relaxation time means are reported for CSF (T1 = 4273.4 ms; T2 = 1577.6 ms; proton density = 107.5 pu), spinal cord (T1 = 780.2 ms; T2 = 101.6 ms; proton density = 58.7 pu), normal disc (T1 = 1164.9 ms; T2 = 101.9 ms; proton density = 78.9 pu), intermediately hydrated disc (T1 = 723 ms; T2 = 66.8 ms; proton density = 60.8 pu), desiccated disc (T1 = 554.4 ms; T2 = 55.6 ms; proton density = 47.6 ms), and vertebral body (T1 = 515.3 ms; T2 = 100.8 ms; proton density = 91.1 pu). Comparisons among the mean T1, T2, and proton density values showed significant differences between different spinal levels (cervical, dorsal, lumbar, and sacral) for CSF (proton density), spinal cord (T2 and proton density), normal disc (T1, T2, and proton density), and vertebral bodies (T1 and proton density). Significant differences were found among mean T1, T2, and proton density values of normal, intermediately hydrated, and desiccated discs. CONCLUSIONS: Measurements can be easily obtained on SyMRI and correlated with previously published values obtained using conventional relaxometry techniques.
BACKGROUND AND PURPOSE: SyMRI is a technique developed to perform quantitative MR imaging. Our aim was to analyze its potential use for measuring relaxation times of normal components of the spine and to compare them with values found in the literature using relaxometry and other techniques. MATERIALS AND METHODS: Thirty-two spine MR imaging studies (10 cervical, 5 dorsal, 17 lumbosacral) were included. A modified multiple-dynamic multiple-echo sequence was added and processed to obtain quantitative T1 (millisecond), T2 (millisecond), and proton density (percentage units [pu]) maps for each patient. An ROI was placed on representative areas for CSF, spinal cord, intervertebral discs, and vertebral bodies, to measure their relaxation. RESULTS: Relaxation time means are reported for CSF (T1 = 4273.4 ms; T2 = 1577.6 ms; proton density = 107.5 pu), spinal cord (T1 = 780.2 ms; T2 = 101.6 ms; proton density = 58.7 pu), normal disc (T1 = 1164.9 ms; T2 = 101.9 ms; proton density = 78.9 pu), intermediately hydrated disc (T1 = 723 ms; T2 = 66.8 ms; proton density = 60.8 pu), desiccated disc (T1 = 554.4 ms; T2 = 55.6 ms; proton density = 47.6 ms), and vertebral body (T1 = 515.3 ms; T2 = 100.8 ms; proton density = 91.1 pu). Comparisons among the mean T1, T2, and proton density values showed significant differences between different spinal levels (cervical, dorsal, lumbar, and sacral) for CSF (proton density), spinal cord (T2 and proton density), normal disc (T1, T2, and proton density), and vertebral bodies (T1 and proton density). Significant differences were found among mean T1, T2, and proton density values of normal, intermediately hydrated, and desiccated discs. CONCLUSIONS: Measurements can be easily obtained on SyMRI and correlated with previously published values obtained using conventional relaxometry techniques.
Authors: Hongbae Jeong; Georgios Ntolkeras; Michel Alhilani; Seyed Reza Atefi; Lilla Zöllei; Kyoko Fujimoto; Ali Pourvaziri; Michael H Lev; P Ellen Grant; Giorgio Bonmassar Journal: PLoS One Date: 2021-01-13 Impact factor: 3.240
Authors: T Yamamoto; C Lacheret; H Fukutomi; R A Kamraoui; L Denat; B Zhang; V Prevost; L Zhang; A Ruet; B Triaire; V Dousset; P Coupé; T Tourdias Journal: AJNR Am J Neuroradiol Date: 2022-07-28 Impact factor: 4.966
Authors: Sana Boudabbous; Emilie Nicodème Paulin; Bénédicte Marie Anne Delattre; Marion Hamard; Maria Isabel Vargas Journal: Insights Imaging Date: 2021-12-04
Authors: Silvan Büeler; Marios C Yiannakas; Zdravko Damjanovski; Patrick Freund; Martina D Liechti; Gergely David Journal: Sci Rep Date: 2022-10-03 Impact factor: 4.996