Literature DB >> 29495929

Lipoproteins for therapeutic delivery: recent advances and future opportunities.

Sangram Raut1, Jean-Louis Dasseux2, Nirupama A Sabnis1, Linda Mooberry1, Andras Lacko1,3.   

Abstract

The physiological role(s) of mammalian plasma lipoproteins is to transport hydrophobic molecules (primarily cholesterol and triacylglycerols) to their respective destinations. Lipoproteins have also been studied as drug-delivery agents due to their advantageous payload capacity, long residence time in the circulation and biocompatibility. The purpose of this review is to briefly discuss current findings with the focus on each type of formulation's potential for clinical applications. Regarding utilizing lipoprotein type formulation for cancer therapeutics, their potential for tumor-selective delivery is also discussed.

Entities:  

Keywords:  HDL; LDL; cancer therapy; discoidal nanoparticles; drug delivery; lipoproteins; rHDL

Mesh：

Substances：

Year:  2018        PMID： 29495929     DOI： 10.4155/tde-2017-0122

Source DB:  PubMed          Journal:  Ther Deliv        ISSN： 2041-5990


  7 in total

Review 1.  Reconstituted Discoidal High-Density Lipoproteins: Bioinspired Nanodiscs with Many Unexpected Applications.

Authors:  Maki Tsujita; Anna Wolska; Daniel A P Gutmann; Alan T Remaley
Journal:  Curr Atheroscler Rep       Date:  2018-11-05       Impact factor: 5.113

Review 2.  Apolipoprotein mimetics in cancer.

Authors:  Samuel C Delk; Arnab Chattopadhyay; Joan Carles Escola-Gil; Alan M Fogelman; Srinivasa T Reddy
Journal:  Semin Cancer Biol       Date:  2020-11-11       Impact factor: 17.012

Review 3.  Use of Nanoparticles in Tissue Engineering and Regenerative Medicine.

Authors:  Milad Fathi-Achachelouei; Helena Knopf-Marques; Cristiane Evelise Ribeiro da Silva; Julien Barthès; Erhan Bat; Aysen Tezcaner; Nihal Engin Vrana
Journal:  Front Bioeng Biotechnol       Date:  2019-05-24

Review 4.  Lipoprotein Drug Delivery Vehicles for Cancer: Rationale and Reason.

Authors:  Jaideep Chaudhary; Joseph Bower; Ian R Corbin
Journal:  Int J Mol Sci       Date:  2019-12-15       Impact factor: 5.923

Review 5.  High Density Lipoproteins: Metabolism, Function, and Therapeutic Potential.

Authors:  Anne Jomard; Elena Osto
Journal:  Front Cardiovasc Med       Date:  2020-03-31

Review 6.  Roles of Reconstituted High-Density Lipoprotein Nanoparticles in Cardiovascular Disease: A New Paradigm for Drug Discovery.

Authors:  Jiansheng Huang; Dongdong Wang; Li-Hao Huang; Hui Huang
Journal:  Int J Mol Sci       Date:  2020-01-23       Impact factor: 5.923

Review 7.  RNAs on the Go: Extracellular Transfer in Insects with Promising Prospects for Pest Management.

Authors:  Dulce Santos; Simon Remans; Stijn Van den Brande; Jozef Vanden Broeck
Journal:  Plants (Basel)       Date:  2021-03-04
  7 in total

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