| Literature DB >> 29494830 |
Indu Yadav1, Suraj K Nayak1, V S Sharan Rathnam1, Indranil Banerjee1, Sirsendu S Ray1, Arfat Anis2, Kunal Pal3.
Abstract
The current study deals with the preparation and the characterization of the PVA-CMT-GO films. The PVA-CMT film was translucent in nature and smooth to touch. The addition of GO resulted in the formation of agglomerated structures. XRD studies suggested that the incorporation of GO increased the average crystallite size. The mechanical properties of the films as determined by stress relaxation studies suggested that all the films were viscoelastic in nature. The drug release study showed a decrease in the amount of the drug release with the increase in the GO content. The PVA-CMT-GO films (without drug) showed certain degree of antimicrobial activity owing to the inherent antimicrobial property of GO. The drug loaded films also showed good antimicrobial property. It was found that the prepared films altered the cell proliferation of the human skin keratinocytes in a composition-dependent manner.Entities:
Keywords: Antimicrobial activity; Carboxymethyl tamarind gum; Cell proliferation; Drug release; Films; Graphene oxide; Polyvinyl alcohol; Viscoelastic
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Year: 2018 PMID： 29494830 DOI： 10.1016/j.jmbbm.2018.02.021
Source DB: PubMed Journal: J Mech Behav Biomed Mater ISSN： 1878-0180