Ilkay Kilic Muftuoglu1,2, Raouf Gaber1,3, Dirk-Uwe Bartsch1, Amit Meshi1, Michael Goldbaum4, William R Freeman5,6. 1. Department of Ophthalmology, Jacobs Retina Center at the Shiley Eye Institute, University of California San Diego, La Jolla, CA, USA. 2. Department of Ophthalmology, Istanbul Training and Research Hospital, Istanbul, Turkey. 3. Also affiliated with Department of Ophthalmology, Tanta University, Tanta, Egypt. 4. Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, CA, USA. 5. Department of Ophthalmology, Jacobs Retina Center at the Shiley Eye Institute, University of California San Diego, La Jolla, CA, USA. freeman@eyecenter.ucsd.edu. 6. Jacobs Retina Center, Shiley Eye Institute, University of California San Diego, 9415 Campus Point Drive, La Jolla, CA, 92037, USA. freeman@eyecenter.ucsd.edu.
Abstract
PURPOSE: Our purpose was to compare the characteristics of the retinal and choroidal lesions including choroidal nevus, choroidal melanoma and congenital hypertrophy of the retina pigment epithelium using conventional color fundus photography (CFP) and multicolor imaging (MCI). METHODS: The paired images of patients with retinal or choroidal lesions were assessed for the visibility of lesion's border, halo and drusen using a grading scale (0-2). The area of the lesion was measured on both imaging modalities. The same grading was also done on the individual color channels of MCI for a further evaluation. RESULTS: Thirty-three eyes of 33 patients were included. There were no significant differences in the mean border, drusen and halo visibility scores between the two imaging modalities (p = 0.12, p = 0.70, p = 0.35). However, the mean area of the lesion was significantly smaller on MCI than that on CFP (14.9±3.3 versus 18.7±3.4 mm2, p = 0.01). CONCLUSION: The appearance of choroidal and/ or retinal lesions on MCI may be different than that on CFP. Though MCI can provide similar information with CFP for the features of retinal and/ or choroidal lesions including border, halo and drusen; the infrared light reflection on MCI underestimates the extent of the choroidal lesion by 33%.
PURPOSE: Our purpose was to compare the characteristics of the retinal and choroidal lesions including choroidal nevus, choroidal melanoma and congenital hypertrophy of the retina pigment epithelium using conventional color fundus photography (CFP) and multicolor imaging (MCI). METHODS: The paired images of patients with retinal or choroidal lesions were assessed for the visibility of lesion's border, halo and drusen using a grading scale (0-2). The area of the lesion was measured on both imaging modalities. The same grading was also done on the individual color channels of MCI for a further evaluation. RESULTS: Thirty-three eyes of 33 patients were included. There were no significant differences in the mean border, drusen and halo visibility scores between the two imaging modalities (p = 0.12, p = 0.70, p = 0.35). However, the mean area of the lesion was significantly smaller on MCI than that on CFP (14.9±3.3 versus 18.7±3.4 mm2, p = 0.01). CONCLUSION: The appearance of choroidal and/ or retinal lesions on MCI may be different than that on CFP. Though MCI can provide similar information with CFP for the features of retinal and/ or choroidal lesions including border, halo and drusen; the infrared light reflection on MCI underestimates the extent of the choroidal lesion by 33%.
Entities:
Keywords:
Choroidal melanoma; Choroidal nevus; Congenital hypertrophy of the retina pigment epithelium; Fundus photography; Multicolor imaging; Pseudocolor
Authors: Ioanna Tsioti; Xuan Liu; Petra Schwarzer; Martin S Zinkernagel; Despina Kokona Journal: Int J Ophthalmol Date: 2022-06-18 Impact factor: 1.645
Authors: Melina Cavichini; Cheolhong An; Dirk-Uwe G Bartsch; Mahima Jhingan; Manuel J Amador-Patarroyo; Christopher P Long; Junkang Zhang; Yiqian Wang; Alison X Chan; Samantha Madala; Truong Nguyen; William R Freeman Journal: Transl Vis Sci Technol Date: 2020-10-20 Impact factor: 3.048