| Literature DB >> 29492639 |
In Yeub Hwang1, Anh Duc Nguyen1, Thu Thi Nguyen1, Linh Thanh Nguyen1, Ok Kyung Lee1, Eun Yeol Lee2.
Abstract
Methane is a promising next-generation carbon feedstock for industrial biotechnology due to its low price and huge availability. Biological conversion of methane to valuable products can mitigate methane-induced global warming as greenhouse gas. There have been challenges for the conversion of methane into various chemicals and fuels using engineered non-native hosts with synthetic methanotrophy or methanotrophs with the reconstruction of synthetic pathways for target products. Herein, we analyze the technical challenges and issues of potent methane bioconversion technology. Pros and cons of metabolic engineering of methanotrophs for methane bioconversion, and perspectives on the bioconversion of methane to chemicals and liquid fuels are discussed.Entities:
Keywords: Metabolic engineering; Methane bioconversion; Methanotrophs; Synthetic methanotrophy
Mesh：
Substances：
Year: 2018 PMID： 29492639 DOI： 10.1007/s00253-018-8842-7
Source DB: PubMed Journal: Appl Microbiol Biotechnol ISSN： 0175-7598 Impact factor: 4.813