Literature DB >> 2948744

T8 cell suppression of antigen- and mitogen-induced T4 cell dependent immunoglobulin production.

E Nilsson, L V von Stedingk, G Biberfeld.   

Abstract

The suppressor effect of T8 cells on antigen-induced, as compared to pokeweed mitogen-induced, T4 cell dependent immunoglobulin (Ig) production by B cells of healthy subjects was studied. The antigens used were purified protein derivative of tuberculin (PPD) and tetanus toxoid (TT). The suppressor effect of T8 cells on IgG, IgM and IgA responses in co-cultures of T4 cells and B cells was significantly stronger in the pokeweed mitogen driven system than in PPD- and TT-driven cultures under the same experimental conditions.

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Year:  1986        PMID： 2948744      PMCID： PMC1542642     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  22 in total

1.  Restimulation of PPD-stimulated lymphocytes: decreased responsiveness of prestimulated cells to a second challenge with PPD and PHA.

Authors:  L Sörén; R Maller
Journal:  Scand J Immunol       Date:  1979       Impact factor: 3.487

2.  The response of lymphocytes from tuberculin-positive or negative humans to various doses of PPD-tuberculin in vitro.

Authors:  B S Nilsson
Journal:  Cell Immunol       Date:  1972-03       Impact factor: 4.868

Review 3.  Regulation of human B cell activation.

Authors:  R S Geha
Journal:  Immunol Rev       Date:  1979       Impact factor: 12.988

4.  Soluble antigen-primed inducer T cells activate antigen-specific suppressor T cells in the absence of antigen-pulsed accessory cells: phenotypic definition of suppressor-inducer and suppressor-effector cells.

Authors:  N K Damle; N Mohagheghpour; E G Engleman
Journal:  J Immunol       Date:  1984-02       Impact factor: 5.422

5.  In vitro induction of human suppressor T cells by mycobacterial antigens. BCG activated OKT4+ cells mediate suppression of antigen induced T cell proliferation.

Authors:  A S Mustafa; T Godal
Journal:  Clin Exp Immunol       Date:  1983-04       Impact factor: 4.330

Review 6.  Polyclonal B-cell activators in the study of the regulation of immunoglobulin synthesis in the human system.

Authors:  T A Waldmann; S Broder
Journal:  Adv Immunol       Date:  1982       Impact factor: 3.543

7.  T lymphocyte subpopulations defined by monoclonal antibodies in synovial fluid of patients with rheumatic disease.

Authors:  E Nilsson; G Biberfeld
Journal:  J Clin Lab Immunol       Date:  1982-11

Review 8.  Immunoregulatory T cell subpopulations in man: dissection by monoclonal antibodies and Fc-receptors.

Authors:  R E Ballieux; C J Heijnen
Journal:  Immunol Rev       Date:  1983       Impact factor: 12.988

9.  The proliferative response of human lymphocytes to antigen is suppressed preferentially by lymphocytes precultured with the same antigen.

Authors:  W Borkowsky; F T Valentine
Journal:  J Immunol       Date:  1979-05       Impact factor: 5.422

10.  The specificity of T-cell helper factor in man.

Authors:  R S Geha; F Mudawwar; E Schneeberger
Journal:  J Exp Med       Date:  1977-06-01       Impact factor: 14.307
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  1 in total

1.  Immunoregulatory function of T8 and T4 cells from synovial fluid of patients with chronic arthritis.

Authors:  E Nilsson; L V von Stedingk; G Biberfeld
Journal:  Agents Actions       Date:  1986-12
  1 in total

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