Literature DB >> 29485449

Recurrent Medullary Thyroid Carcinoma on 68Ga-Prostate-Specific Membrane Antigen PET/CT: Exploring New Theranostic Avenues.

Saurabh Arora1, Nishikant Avinash Damle, Girish Kumar Parida, Abhinav Singhal, Harish Nalli, Shreya Dattagupta, Chandrasekar Bal.   

Abstract

The prostate-specific membrane antigen (PSMA) is highly expressed in prostate cancer cells. Few other malignancies have shown expression of PSMA. We present a case of 35-year-old man with medullary thyroid carcinoma, post total thyroidectomy and bilateral neck dissection, now presenting with rising calcitonin levels (doubling time 9 months) and local neck recurrence with negative I-MIBG scan. We decided to perform Ga-PSMA-HBED-CC PET/CT scan to assess PSMA expression and explore the therapeutic option in view of rising serum calcitonin. It revealed intense PSMA uptake in the soft tissue mass in left thyroid bed and cervical lymph nodes.

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Year:  2018        PMID： 29485449     DOI： 10.1097/RLU.0000000000002010

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN： 0363-9762            Impact factor:   7.794


  5 in total

1.  Immunohistochemical Reactivity of Prostate-Specific Membrane Antigen in Salivary Gland Tumors.

Authors:  Haruto Nishida; Yoshihiko Kondo; Takahiro Kusaba; Hiroko Kadowaki; Tsutomu Daa
Journal:  Head Neck Pathol       Date:  2021-08-21

Review 2.  PET-CT in Clinical Adult Oncology-V. Head and Neck and Neuro Oncology.

Authors:  Richard H Wiggins; John M Hoffman; Gabriel C Fine; Matthew F Covington; Ahmed Ebada Salem; Bhasker R Koppula; Kathryn A Morton
Journal:  Cancers (Basel)       Date:  2022-05-31       Impact factor: 6.575

3.  Nonspecific Uptake of 68Ga-Prostate-Specific Membrane Antigen in Diseases other than Prostate Malignancy on Positron Emission Tomography/Computed Tomography Imaging: A Pictorial Assay and Review of Literature.

Authors:  Dharmender Malik; Apurva Sood; Bhagwant Rai Mittal; Harmandeep Singh; Rajender Kumar Basher; Jaya Shukla; Anish Bhattacharya; Shrawan Kumar Singh
Journal:  Indian J Nucl Med       Date:  2018 Oct-Dec

Review 4.  New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms.

Authors:  Emilia Fortunati; Giulia Argalia; Lucia Zanoni; Stefano Fanti; Valentina Ambrosini
Journal:  Curr Treat Options Oncol       Date:  2022-03-24

Review 5.  PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports.

Authors:  M J M Uijen; Y H W Derks; W A M van Gemert; J Nagarajah; R I J Merkx; M G M Schilham; J Roosen; B M Privé; S A M van Lith; C M L van Herpen; M Gotthardt; S Heskamp
Journal:  Eur J Nucl Med Mol Imaging       Date:  2021-06-12       Impact factor: 9.236
  5 in total

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